OSGIN1 and MEIS2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		OSGIN1	MEIS2
Description		oxidative stress induced growth inhibitor 1	Meis homeobox 2
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nuclear Chromatin Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Growth Factor Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding
	Biological Process	Signal Transduction Multicellular Organism Development Cell Differentiation Negative Regulation Of Cell Growth Regulation Of Cell Migration Regulation Of Cell Proliferation Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Transcription By RNA Polymerase II Visual Learning Response To Mechanical Stimulus Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		LDL cholesterol ( 30275531) Pursuit maintenance gain ( 29064472) Response to platinum-based neoadjuvant chemotherapy in cervical cancer ( 28120872)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		23 interacting genes: AKT1 ATM BCAR3 CAPN3 CCDC33 CRX DNAJA3 FGFR4 IKZF3 INCA1 KRAS LNX1 MEIS2 MEOX2 PPM1D PTEN REL SAXO1 SMARCB1 TCF12 TCF4 TLE5 XRCC3	14 interacting genes: ANXA1 APP ARNT2 C1orf94 CCDC196 DGCR6 HOXA13 HOXA9 OSGIN1 PBX1 RBPMS SQSTM1 TRIM25 ZNHIT3
Entrez ID		29948	4212
HPRD ID		06412	03443
Ensembl ID		ENSG00000140961	ENSG00000134138
Uniprot IDs		Q9UJX0	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs			3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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