EFHC2 and PLOD3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		EFHC2	PLOD3
Description		EF-hand domain containing 2	procollagen-lysine,2-oxoglutarate 5-dioxygenase 3
Image
GO Annotations	Cellular Component	Microtubule	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity
	Biological Process	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Oxidation-reduction Process Lung Morphogenesis Basement Membrane Assembly
Pathways			Collagen biosynthesis and modifying enzymes
Drugs			Vitamin C Succinic acid
Diseases
GWAS		Mean arterial pressure ( 29403010)	Blood protein levels ( 30072576)
Interacting Genes		37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4	9 interacting genes: CCDC85B DPPA2 EFHC2 EHMT2 FAM153A LINC00839 RAB3IP RHOU RHOXF2
Entrez ID		80258	8985
HPRD ID		06540	04347
Ensembl ID		ENSG00000183690	ENSG00000106397
Uniprot IDs		Q5JST6	O60568 Q9UG85
PDB IDs		2Z13 2Z14	6FXK 6FXM 6FXR 6FXT 6FXX 6FXY
Enriched GO Terms of Interacting Partners?
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