PLOD3 and RAB3IP

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid, two hybrid)

		PLOD3	RAB3IP
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	RAB3A interacting protein
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GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome	Nucleus Cytosol Cytoskeleton Lamellipodium
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity	Protein Binding Rab Guanyl-nucleotide Exchange Factor Activity
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Oxidation-reduction Process Lung Morphogenesis Basement Membrane Assembly	Protein Targeting To Membrane Ciliary Basal Body-plasma Membrane Docking
Pathways		Collagen biosynthesis and modifying enzymes	Anchoring of the basal body to the plasma membrane VxPx cargo-targeting to cilium BBSome-mediated cargo-targeting to cilium RAB GEFs exchange GTP for GDP on RABs
Drugs		Vitamin C Succinic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Diastolic blood pressure ( 27841878) Height ( 28552196) Logical memory (delayed recall) in normal cognition ( 29274321)
Interacting Genes		9 interacting genes: CCDC85B DPPA2 EFHC2 EHMT2 FAM153A LINC00839 RAB3IP RHOU RHOXF2	21 interacting genes: BANP CHCHD3 FAM124A KRT40 MVP NAA10 PLOD3 PPL RAB11A RAB3A RAB3D RAB3IL1 RAB8A RAB8B RUFY1 SFN SSX2 SUV39H2 TRAPPC6A TXNDC5 ZNF410
Entrez ID		8985	117177
HPRD ID		04347	10565
Ensembl ID		ENSG00000106397	ENSG00000127328
Uniprot IDs		O60568 Q9UG85	Q96QF0
PDB IDs		6FXK 6FXM 6FXR 6FXT 6FXX 6FXY	4LHX 4LHY 4LHZ 4UJ3 4UJ4 4UJ5 6F6P
Enriched GO Terms of Interacting Partners?
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