ZMIZ2 and SOCS6

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		ZMIZ2	SOCS6
Description		zinc finger MIZ-type containing 2	suppressor of cytokine signaling 6
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Mitochondrion Nuclear Replication Fork	Immunological Synapse Cytoplasm Cytosol Phosphatidylinositol 3-kinase Complex
	Molecular Function	RNA Polymerase II Transcription Factor Binding Transcription Coregulator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity SUMO Ligase Activity	Protein Binding 1-phosphatidylinositol-3-kinase Regulator Activity
	Biological Process	Regulation Of Transcription By RNA Polymerase II Transforming Growth Factor Beta Receptor Signaling Pathway Protein Sumoylation Positive Regulation Of Transcription By RNA Polymerase II Chromatin-mediated Maintenance Of Transcription SMAD Protein Signal Transduction	Defense Response JAK-STAT Cascade Negative Regulation Of Signal Transduction Proteasomal Protein Catabolic Process Protein Ubiquitination Intracellular Signal Transduction Regulation Of Growth Regulation Of Phosphatidylinositol 3-kinase Activity Post-translational Protein Modification Phosphatidylinositol Phosphorylation Negative Regulation Of T Cell Activation
Pathways			Regulation of KIT signaling Neddylation
Drugs
Diseases
GWAS		General cognitive ability ( 29844566) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Mean corpuscular hemoglobin ( 27863252) Red blood cell count ( 27863252)	Diverticular disease ( 30177863) Night sleep phenotypes ( 27126917) Systemic lupus erythematosus ( 18204098) Type 2 diabetes ( 29621232)
Interacting Genes		21 interacting genes: AR ARSJ ASB13 BANP C2orf88 CRCP INTS4 LRRC37A11P MCPH1 MVP NBL1 PIAS3 PIN1 RANBP3 SALL2 SCAMP1 SELENOV SOCS6 SSX2 TP53 TRAPPC6A	31 interacting genes: ACVR1 APPL1 BMPR1B CLNK CRK DAB1 EFEMP1 EGFR ELOB ELOC FRS3 INSR IRS2 IRS4 KDM1A KIT LNX1 PIK3R1 PIK3R2 PIK3R3 PITRM1 RBCK1 RELA SMURF2 TGFBR1 TUBA1A TUBB4B UBE2D2 UBE2I WDR89 ZMIZ2
Entrez ID		83637	9306
HPRD ID		13225	05491
Ensembl ID		ENSG00000122515	ENSG00000170677
Uniprot IDs		E7EWM3 Q8NF64	A0A024R379 O14544
PDB IDs			2VIF
Enriched GO Terms of Interacting Partners?
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