MID1 and EHHADH

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MID1	EHHADH
Description		midline 1	enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase
Image			No pdb structure
GO Annotations	Cellular Component	Spindle Cytosol Microtubule Microtubule Associated Complex Cytoplasmic Microtubule	Peroxisome Peroxisomal Matrix Cytosol
	Molecular Function	Protein Binding Microtubule Binding Zinc Ion Binding Transferase Activity Enzyme Binding Ubiquitin Protein Ligase Binding Identical Protein Binding Protein Homodimerization Activity Phosphoprotein Binding	3-hydroxyacyl-CoA Dehydrogenase Activity Dodecenoyl-CoA Delta-isomerase Activity Enoyl-CoA Hydratase Activity Protein Binding Long-chain-enoyl-CoA Hydratase Activity Enzyme Binding
	Biological Process	Microtubule Cytoskeleton Organization Negative Regulation Of Microtubule Depolymerization Pattern Specification Process Positive Regulation Of Stress-activated MAPK Cascade Protein Localization To Microtubule Interferon-gamma-mediated Signaling Pathway	Internal Protein Amino Acid Acetylation Protein Targeting To Peroxisome Fatty Acid Beta-oxidation Fatty Acid Beta-oxidation Using Acyl-CoA Oxidase
Pathways		Interferon gamma signaling	Beta-oxidation of very long chain fatty acids Peroxisomal protein import Peroxisomal protein import
Drugs			NADH
Diseases		Opitz-GBBB syndrome
GWAS			Cognitive performance ( 19734545) Major depressive disorder ( 27519822 21042317)
Interacting Genes		33 interacting genes: BYSL DYRK4 EHHADH FKBP1A GMCL1 HMG20B HTT IGBP1 MEOX1 MID1IP1 MID2 OTUB2 PAX6 PKN1 PPP2CA PPP2CB PTPA SPAG5 STK36 TCEANC UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E2 UBE2E3 UBE2K UBE2L3 UBE2N UBE2V1 UBE2W UBTD1	27 interacting genes: ACTB ACTG1 BHLHE40 CAT CBS CCDC102B DES FUNDC1 KCTD6 KCTD9 KRTAP10-7 LZTS2 MID1 NECAB2 PNMA1 SCP2 SSNA1 SSX2IP TNIP1 TPP2 TRAF1 TRIM27 TRIM41 TRIM54 TRIM55 TRIM63 ZBTB9
Entrez ID		4281	1962
HPRD ID		02047	06125
Ensembl ID		ENSG00000101871	ENSG00000113790
Uniprot IDs		A0A024RBV4 A0A087X0X0 A0A087X255 O15344	Q08426
PDB IDs		2DQ5 2FFW 2JUN 5IM8
Enriched GO Terms of Interacting Partners?
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