TNNT1 and SERPINA4

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TNNT1	SERPINA4
Description		troponin T1, slow skeletal type	serpin family A member 4
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Extracellular Region Extracellular Space Platelet Dense Granule Lumen Extracellular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding	Serine-type Endopeptidase Inhibitor Activity
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction	Platelet Degranulation Negative Regulation Of Endopeptidase Activity
Pathways		Striated Muscle Contraction	Platelet degranulation
Drugs			Zinc Copper
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Blood protein levels ( 30072576 29875488 28240269) Vaspin levels ( 22907691)
Interacting Genes		61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	13 interacting genes: CTSD GADD45G ILK KLK1 KLK2 MAP4K2 MAPK6 NR4A1 RASA1 TAB1 TNFRSF14 TNNT1 YAE1
Entrez ID		7138	5267
HPRD ID		01841	01004
Ensembl ID		ENSG00000105048	ENSG00000100665
Uniprot IDs		P13805	A0A024R6I9 P29622
PDB IDs			6F02
Enriched GO Terms of Interacting Partners?
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