TNNT1 and SNW1

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TNNT1	SNW1
Description		troponin T1, slow skeletal type	SNW domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Nucleus Nucleoplasm Spliceosomal Complex Cyclin/CDK Positive Transcription Elongation Factor Complex Nuclear Matrix Nuclear Body Nuclear Speck U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding	Transcription Coactivator Activity Transcription Corepressor Activity RNA Binding Notch Binding Protein Binding Enzyme Binding Nuclear Hormone Receptor Binding Vitamin D Receptor Binding Retinoic Acid Receptor Binding SMAD Binding Androgen Receptor Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction	Negative Regulation Of Transcription By RNA Polymerase II MRNA Splicing, Via Spliceosome Regulation Of Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Notch Signaling Pathway Positive Regulation Of Transcription Of Notch Receptor Target Viral Process Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation By Host Of Viral Transcription Positive Regulation Of Notch Signaling Pathway Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of MRNA Splicing, Via Spliceosome Retinoic Acid Receptor Signaling Pathway Regulation Of Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Neurogenesis Positive Regulation Of Histone H3-K4 Methylation Regulation Of Vitamin D Receptor Signaling Pathway Positive Regulation Of Vitamin D Receptor Signaling Pathway Cellular Response To Retinoic Acid
Pathways		Striated Muscle Contraction	Pre-NOTCH Transcription and Translation Pre-NOTCH Transcription and Translation Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells NOTCH1 Intracellular Domain Regulates Transcription NOTCH1 Intracellular Domain Regulates Transcription SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Constitutive Signaling by NOTCH1 PEST Domain Mutants Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants Notch-HLH transcription pathway mRNA Splicing - Major Pathway RUNX3 regulates NOTCH signaling RUNX3 regulates NOTCH signaling NOTCH3 Intracellular Domain Regulates Transcription NOTCH3 Intracellular Domain Regulates Transcription NOTCH4 Intracellular Domain Regulates Transcription
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)	Response to platinum-based chemotherapy in non-small-cell lung cancer ( 22872573)
Interacting Genes		61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	61 interacting genes: ACTN2 ASCC2 CEP55 CIR1 CXorf56 DAXX EP300 GOLGA2 HDAC2 IKBKG IKZF1 JDP2 KRT40 LRP2BP LZTS2 MAGEA1 MAPK6 MEN1 MFAP1 MSL1 MTUS2 NCOA1 NCOR1 NCOR2 NOTCH1 NOTCH3 NR0B1 NR0B2 OCLN PABPN1 PCBD2 PGR PPIL1 PRKAA2 RARA RB1 RBL1 RBL2 RBPJ RINT1 RXRA SART1 SIN3A SIRT1 SKI SMAD2 SMAD3 SMAD4 SNRNP200 SNU13 TEX11 TFIP11 TNNT1 TOP1 TRAF1 TRIM15 TTC14 VAV2 VDR VPS39 ZSCAN1
Entrez ID		7138	22938
HPRD ID		01841	04340
Ensembl ID		ENSG00000105048	ENSG00000100603
Uniprot IDs		P13805	G3V3A4 Q13573
PDB IDs			5MQF 5XJC 5YZG 5Z58 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV
Enriched GO Terms of Interacting Partners?
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