TNNT1 and ARMC8

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		TNNT1	ARMC8
Description		troponin T1, slow skeletal type	armadillo repeat containing 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytosol Troponin Complex	Ubiquitin Ligase Complex Extracellular Region Nucleus Cytoplasm GID Complex Specific Granule Lumen Tertiary Granule Lumen
	Molecular Function	Calcium Ion Binding Protein Binding Tropomyosin Binding Calcium-dependent ATPase Activity Troponin T Binding	Protein Binding
	Biological Process	Skeletal Muscle Contraction Muscle Contraction Transition Between Fast And Slow Fiber Muscle Filament Sliding Slow-twitch Skeletal Muscle Fiber Contraction Sarcomere Organization Negative Regulation Of Muscle Contraction Cardiac Muscle Contraction	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Neutrophil Degranulation
Pathways		Striated Muscle Contraction	Neutrophil degranulation
Drugs
Diseases		Nemaline myopathy
GWAS		Height ( 31562340)
Interacting Genes		61 interacting genes: ARMC8 BLOC1S2 BMPR1B CCDC136 CCDC85B CHD3 DDX5 EEF1G FAF1 FXR2 FYN HAP1 HMGXB4 HSP90AB1 IMMT KAT5 KRT40 LARP1 LDOC1 MARS1 MORF4L1 NACAD NAGK NFE2L2 NINL NSG2 OSBP2 OSM PI4KA PLEKHF1 PNMA1 PPFIA1 PRKG1 PSMC5 SEC31A SERPINA4 SH3GL3 SMAD1 SMAD2 SMURF1 SNW1 TBPL1 TFIP11 TGFBR1 TMEM98 TNNC1 TNNI1 TNNI2 TNNI3 TPM1 TPM3 TRA2A TRIM63 UBE2D1 VIM WDCP ZC3H15 ZKSCAN5 ZMYND19 ZNF250 ZNF768	4 interacting genes: CTNNA1 MAEA TCF12 TNNT1
Entrez ID		7138	25852
HPRD ID		01841	09992
Ensembl ID		ENSG00000105048	ENSG00000114098
Uniprot IDs		P13805	B7Z637 Q8IUR7
PDB IDs
Enriched GO Terms of Interacting Partners?
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