THY1 and ATXN1L

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)

		THY1	ATXN1L
Description		Thy-1 cell surface antigen	ataxin 1 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cell Endoplasmic Reticulum Cytosol Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Cell Surface Apical Plasma Membrane Dendrite Growth Cone Axolemma Anchored Component Of External Side Of Plasma Membrane Dendrite Membrane Neuronal Cell Body Membrane Membrane Raft Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Dendrite
	Molecular Function	GTPase Activator Activity Integrin Binding Protein Binding Protein Kinase Binding GPI Anchor Binding	DNA Binding RNA Binding Protein Binding
	Biological Process	Angiogenesis Regulation Of Cell-matrix Adhesion Positive Regulation Of Cellular Extravasation Negative Regulation Of Protein Kinase Activity Cytoskeleton Organization Integrin-mediated Signaling Pathway Cell-cell Signaling Negative Regulation Of Cell Migration Positive Regulation Of Heterotypic Cell-cell Adhesion Receptor Clustering Positive Regulation Of GTPase Activity Retinal Cone Cell Development Protein Autophosphorylation Focal Adhesion Assembly Negative Regulation Of Axonogenesis T Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Focal Adhesion Assembly Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Neuron Projection Regeneration Cell-cell Adhesion Regulation Of Rho-dependent Protein Serine/threonine Kinase Activity	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Brain Development Learning Memory Extracellular Matrix Organization Social Behavior Lung Alveolus Development Anatomical Structure Development Positive Regulation Of Hematopoietic Stem Cell Proliferation
Pathways		Post-translational modification: synthesis of GPI-anchored proteins
Drugs
Diseases
GWAS			Response to anti-TNF therapy in rheumatoid arthritis ( 26776603)
Interacting Genes		8 interacting genes: ATXN1L ATXN7 CLK1 FYN ITGAM ITGAV ITGB3 LCK	57 interacting genes: ACO2 ACOT7 ADORA1 AFAP1L2 ALG13 ANKHD1 AP1G2 AP2M1 APBB1 ATXN1 CAMSAP2 CBFA2T2 CHD6 COIL CTBP1 DAB2 DAZAP2 EPB41L2 EPB41L3 FADS2 FUS GAS7 GMEB2 GORASP2 GPATCH8 HGS HIVEP1 HSFX1 MACROH2A1 MATN2 MBD1 MBD6 MEOX2 METTL17 NBR1 NCOR1 NCOR2 NIT1 PHPT1 PICK1 PRRC2B RAD54L2 RBFOX2 RRAGC SCAF11 SMARCC2 SREBF1 ST6GALNAC6 STAC2 SUGP2 THY1 TMEM25 TMEM8B TRIP11 YY1AP1 ZC3H7B ZSWIM8
Entrez ID		7070	342371
HPRD ID		01769	19555
Ensembl ID		ENSG00000154096	ENSG00000224470
Uniprot IDs		B0YJA4 P04216	P0C7T5
PDB IDs
Enriched GO Terms of Interacting Partners?
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