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TERF1 and ASS1
Number of citations of the paper that reports this interaction (PubMedID
21044950
)
41
Data Source:
BioGRID
(two hybrid)
TERF1
ASS1
Description
telomeric repeat binding factor 1
argininosuccinate synthase 1
Image
GO Annotations
Cellular Component
Nuclear Telomere Cap Complex
Nuclear Chromosome, Telomeric Region
Fibrillar Center
Cell
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Spindle
Nuclear Body
Shelterin Complex
Nucleus
Cytoplasm
Mitochondrial Outer Membrane
Lysosome
Endoplasmic Reticulum
Cytosol
Perikaryon
Extracellular Exosome
Cell Body Fiber
Molecular Function
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
DNA Binding
Double-stranded Telomeric DNA Binding
Telomerase Activity
Protein Binding
Microtubule Binding
DNA Binding, Bending
Telomeric DNA Binding
Identical Protein Binding
Protein Homodimerization Activity
Ankyrin Repeat Binding
G-rich Strand Telomeric DNA Binding
RNA Binding
Argininosuccinate Synthase Activity
Protein Binding
ATP Binding
Toxic Substance Binding
Amino Acid Binding
Identical Protein Binding
Biological Process
Telomere Maintenance
Regulation Of Transcription By RNA Polymerase II
Telomere Maintenance Via Telomerase
Negative Regulation Of DNA Replication
Telomere Capping
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication
Response To Drug
Meiotic Telomere Clustering
Cell Division
Negative Regulation Of Telomerase Activity
Telomeric D-loop Disassembly
T-circle Formation
Negative Regulation Of Telomere Maintenance Via Telomere Lengthening
Positive Regulation Of Shelterin Complex Assembly
Negative Regulation Of Establishment Of Protein Localization To Telomere
Negative Regulation Of Establishment Of RNA Localization To Telomere
Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere
Negative Regulation Of Exonuclease Activity
Negative Regulation Of Telomeric D-loop Disassembly
Urea Cycle
Citrulline Metabolic Process
Argininosuccinate Metabolic Process
Kidney Development
Liver Development
Arginine Biosynthetic Process
Aspartate Metabolic Process
Acute-phase Response
Midgut Development
Aging
Response To Nutrient
Circadian Rhythm
Response To Zinc Ion
Response To Mycotoxin
Response To Estradiol
Positive Regulation Of Nitric Oxide Biosynthetic Process
Response To Growth Hormone
Diaphragm Development
Cellular Response To Lipopolysaccharide
Cellular Response To Amino Acid Stimulus
Cellular Response To Ammonium Ion
Cellular Response To CAMP
Cellular Response To Interferon-gamma
Cellular Response To Tumor Necrosis Factor
Cellular Response To Glucagon Stimulus
Cellular Response To Oleic Acid
Cellular Response To Amine Stimulus
Cellular Response To Laminar Fluid Shear Stress
Cellular Response To Dexamethasone Stimulus
Negative Regulation Of Leukocyte Cell-cell Adhesion
Pathways
Recognition and association of DNA glycosylase with site containing an affected pyrimidine
Cleavage of the damaged pyrimidine
Recognition and association of DNA glycosylase with site containing an affected purine
Recognition and association of DNA glycosylase with site containing an affected purine
Cleavage of the damaged purine
Cleavage of the damaged purine
Meiotic synapsis
Packaging Of Telomere Ends
Telomere Extension By Telomerase
DNA Damage/Telomere Stress Induced Senescence
Urea cycle
Drugs
L-Arginine
L-Aspartic Acid
L-Aspartic Acid
L-Citrulline
L-Citrulline
ATP
Diseases
Citrullinemia (CTLN)
GWAS
Crohn's disease (
22412388
)
Leukocyte telomere length (
31171785
)
Interacting Genes
204 interacting genes:
ACAT2
ACOT7
ACY1
AFAP1L2
AHCY
AK1
AKR1A1
ALDOA
AMPD2
AMPH
ANXA2
ANXA5
ANXA8L1
APEX1
ARHGDIA
ARPP21
ASS1
ATM
BCL7B
BIN2
BLM
BRAF
C12orf43
C1orf35
CALD1
CAPNS1
CASP7
CCDC9
CDC6
CEP85
CFL1
CKB
CORO1B
CPNE3
CRYBB1
CRYM
DBN1
DBNL
DCX
DDX19B
DDX21
DDX23
DDX24
DDX39A
DLG5
DNAJB1
DNPH1
DPP3
DPYSL3
EEF1D
EIF4B
ENO2
EPB41L1
EPHX2
EVL
FANCD2
FBP1
FBXO4
FEN1
FES
FKBP8
GAMT
GAPDH
GIT1
GNL3L
GNMT
GSS
H1-1
HCLS1
HDGFL2
HEXIM1
HEXIM2
HGD
HMGN3
HMGN4
HMOX1
HNMT
HOXA3
HSP90AB1
HSPA6
IPO5
JSRP1
KDM1A
KEAP1
KIFBP
KLHDC4
KPNB1
LASP1
LDHA
LDHB
LRSAM1
LYAR
MAP4
MAP7
MAPK12
MAPRE1
MCM2
MDH1
MSN
MT1X
MVK
NAP1L1
NBN
NEFL
NEK7
NME1
NME2
NOL12
NOL3
NUDCD2
NUDT14
NUMA1
NXNL1
OCM2
OGFR
PA2G4
PACSIN2
PAFAH1B3
PAGE2
PAICS
PAK4
PCP4
PEPD
PFKP
PFN2
PGD
PGLS
PGM1
PGM2
PINX1
PKM
PNMT
POT1
PPM1G
PRDX1
PRDX6
PRKCB
PTMA
PTPN5
RBMY1A1
RECQL4
RIC8A
RLIM
RNF10
RPAP3
RPL19
RTN3
RTN4
SALL1
SARS1
SBDS
SENP8
SET
SH3BP1
SH3GL2
SH3GL3
SHFL
SIRPD
SKP1
SMAD9
SMARCC2
SNCG
SOAT1
SP100
SRM
SRSF6
STUB1
SULT1C2
SUPT5H
SYK
TALDO1
TBC1D10A
TBCD
TBL1X
TCIRG1
TERT
THG1L
TINAG
TINF2
TKT
TMSB10
TMSB4Y
TNKS
TNKS2
TNPO2
TOMM34
TPI1
TRIM16
TRIP10
TRMT1
TUBB2A
TUBB3
TUBB4B
UBE2M
UTP14A
WARS1
WDR4
WFS1
YWHAG
ZBTB16
ZC3H18
ZFP36L1
ZHX1
ZNF790
15 interacting genes:
AKTIP
APP
ARAF
ASCC2
ELN
JAK2
MLH1
MT2A
NUP214
PMPCA
PTPN1
STOM
TERF1
TERF2
USP4
Entrez ID
7013
445
HPRD ID
02975
04590
Ensembl ID
ENSG00000147601
ENSG00000130707
Uniprot IDs
P54274
P00966
Q5T6L4
PDB IDs
1BA5
1H6O
1ITY
1IV6
1W0T
3BQO
3L82
5HKP
5WIR
5XUP
2NZ2
Enriched GO Terms of Interacting Partners
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