ASS1 and PMPCA

		ASS1	PMPCA
Description		argininosuccinate synthase 1	peptidase, mitochondrial processing subunit alpha
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber	Extracellular Space Mitochondrion Mitochondrial Inner Membrane Mitochondrial Processing Peptidase Complex
	Molecular Function	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding	Endopeptidase Activity Metalloendopeptidase Activity Metal Ion Binding
	Biological Process	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Zinc Ion Response To Mycotoxin Response To Estradiol Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion	Proteolysis Protein Processing Involved In Protein Targeting To Mitochondrion Mitochondrial Calcium Ion Transmembrane Transport
Pathways		Urea cycle	Mitochondrial protein import Processing of SMDT1
Drugs		L-Arginine L-Aspartic Acid L-Aspartic Acid L-Citrulline L-Citrulline ATP
Diseases		Citrullinemia (CTLN)
GWAS			Chronotype ( 30696823) Crohn's disease ( 28067908) Granulocyte count ( 27863252) Inflammatory bowel disease ( 28067908 23128233) Joint damage in rheumatoid arthritis ( 26498133) Myeloid white cell count ( 27863252) Neutrophil count ( 27863252) Serum total protein level ( 29403010) Sum basophil neutrophil counts ( 27863252) Sum neutrophil eosinophil counts ( 27863252) Ulcerative colitis ( 28067908) White blood cell count ( 27863252)
Interacting Genes		15 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 MLH1 MT2A NUP214 PMPCA PTPN1 STOM TERF1 TERF2 USP4	13 interacting genes: ASS1 AVEN BMPR2 KIF2C NDOR1 NPSR1 NSMF OLFM1 PCDHB4 PMPCB SCUBE1 SKIV2L UBAC1
Entrez ID		445	23203
HPRD ID		04590	07500
Ensembl ID		ENSG00000130707	ENSG00000165688
Uniprot IDs		P00966 Q5T6L4	Q10713
PDB IDs		2NZ2
Enriched GO Terms of Interacting Partners?
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