ASS1 and ELN

Number of citations of the paper that reports this interaction (PubMedID 1372742)
4

Data Source:
HPRD (in vivo)

		ASS1	ELN
Description		argininosuccinate synthase 1	elastin
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrial Outer Membrane Lysosome Endoplasmic Reticulum Cytosol Perikaryon Extracellular Exosome Cell Body Fiber	Extracellular Region Extracellular Matrix Collagen-containing Extracellular Matrix Elastic Fiber
	Molecular Function	RNA Binding Argininosuccinate Synthase Activity Protein Binding ATP Binding Toxic Substance Binding Amino Acid Binding Identical Protein Binding	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Constituent Conferring Elasticity Extracellular Matrix Binding
	Biological Process	Urea Cycle Citrulline Metabolic Process Argininosuccinate Metabolic Process Kidney Development Liver Development Arginine Biosynthetic Process Aspartate Metabolic Process Acute-phase Response Midgut Development Aging Response To Nutrient Circadian Rhythm Response To Zinc Ion Response To Mycotoxin Response To Estradiol Positive Regulation Of Nitric Oxide Biosynthetic Process Response To Growth Hormone Diaphragm Development Cellular Response To Lipopolysaccharide Cellular Response To Amino Acid Stimulus Cellular Response To Ammonium Ion Cellular Response To CAMP Cellular Response To Interferon-gamma Cellular Response To Tumor Necrosis Factor Cellular Response To Glucagon Stimulus Cellular Response To Oleic Acid Cellular Response To Amine Stimulus Cellular Response To Laminar Fluid Shear Stress Cellular Response To Dexamethasone Stimulus Negative Regulation Of Leukocyte Cell-cell Adhesion	Outflow Tract Morphogenesis Aortic Valve Morphogenesis Skeletal Muscle Tissue Development Respiratory Gaseous Exchange Blood Circulation Animal Organ Morphogenesis Extracellular Matrix Organization Regulation Of Actin Filament Polymerization Stress Fiber Assembly Regulation Of Smooth Muscle Cell Proliferation
Pathways		Urea cycle	Degradation of the extracellular matrix Elastic fibre formation Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs		L-Arginine L-Aspartic Acid L-Aspartic Acid L-Citrulline L-Citrulline ATP	Rofecoxib
Diseases		Citrullinemia (CTLN)	Congenital supravalvar aortic stenosis Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS			Diverticular disease ( 30177863) Height ( 31562340)
Interacting Genes		15 interacting genes: AKTIP APP ARAF ASCC2 ELN JAK2 MLH1 MT2A NUP214 PMPCA PTPN1 STOM TERF1 TERF2 USP4	22 interacting genes: ASS1 BGN CKMT2 CLU DCN ELANE FBLN1 FBLN2 FBN1 FBN2 FCN1 FKBP10 LGALS3 LOX LOXL1 LYZ MAGEH1 MFAP2 MTDH NID2 PRTN3 SPINK1
Entrez ID		445	2006
HPRD ID		04590	00556
Ensembl ID		ENSG00000130707	ENSG00000049540
Uniprot IDs		P00966 Q5T6L4	B3KRT8 B4E3S4 E7EN65 E7ENM0 G3V0G6 G5E950 P15502 Q59H17 Q6ZUN2 Q8NBI4
PDB IDs		2NZ2
Enriched GO Terms of Interacting Partners?
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