ACTC1 and SCIN

Number of citations of the paper that reports this interaction (PubMedID 12438125)
4

Data Source:
HPRD (in vivo)

		ACTC1	SCIN
Description		actin alpha cardiac muscle 1	scinderin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse	Podosome Cell Cytoplasm Plasma Membrane Brush Border Cell Cortex Cell Junction Protein-containing Complex Cell Projection Extracellular Exosome
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	Phosphatidylserine Binding Actin Binding Calcium Ion Binding 1-phosphatidylinositol Binding Phosphatidylinositol-4,5-bisphosphate Binding Actin Filament Binding
	Biological Process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Negative Regulation Of Cell Proliferation Calcium Ion Regulated Exocytosis Regulation Of Chondrocyte Differentiation Sequestering Of Actin Monomers Positive Regulation Of Apoptotic Process Actin Nucleation Positive Regulation Of Megakaryocyte Differentiation Actin Filament Severing Positive Regulation Of Secretion Positive Regulation Of Actin Nucleation Actin Filament Capping
Pathways		Striated Muscle Contraction
Drugs
Diseases		Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Axial length ( 24144296) Refractive error ( 20835239)	Height ( 31562340) Metabolite levels ( 23823483) Small cell lung carcinoma ( 28604730)
Interacting Genes		39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	4 interacting genes: ACTA1 ACTC1 ACTG1 UBAP2L
Entrez ID		70	85477
HPRD ID		00015	11539
Ensembl ID		ENSG00000159251	ENSG00000006747
Uniprot IDs		B3KPP5 P68032	Q9Y6U3
PDB IDs			3FG6 5A1K 5A1M
Enriched GO Terms of Interacting Partners?
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