ACTC1 and ANG

Number of citations of the paper that reports this interaction (PubMedID 8127865)
84

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		ACTC1	ANG
Description		actin alpha cardiac muscle 1	angiogenin
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse	Extracellular Region Basement Membrane Extracellular Space Nucleus Nucleolus Actin Cytoskeleton Growth Cone Cytoplasmic Vesicle Angiogenin-PRI Complex Neuronal Cell Body
	Molecular Function	ATP Binding ATPase Activity Myosin Binding	DNA Binding Actin Binding Endonuclease Activity Ribonuclease Activity Signaling Receptor Binding Copper Ion Binding Protein Binding Heparin Binding RRNA Binding Peptide Binding Protein Homodimerization Activity
	Biological Process	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration	Angiogenesis Ovarian Follicle Development Oocyte Maturation Response To Hypoxia Placenta Development Positive Regulation Of Endothelial Cell Proliferation Diacylglycerol Biosynthetic Process Cell Communication Activation Of Phospholipase C Activity RRNA Transcription Response To Hormone Cell Migration Negative Regulation Of Translation Actin Filament Polymerization Activation Of Protein Kinase B Activity Activation Of Phospholipase A2 Activity Adherens Junction Organization Positive Regulation Of Phosphorylation Homeostatic Process Negative Regulation Of Smooth Muscle Cell Proliferation Positive Regulation Of Protein Secretion RNA Phosphodiester Bond Hydrolysis
Pathways		Striated Muscle Contraction	Adherens junctions interactions
Drugs			Pidolic Acid Citric Acid
Diseases		Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)	Amyotrophic lateral sclerosis (ALS); Lou Gehrig's disease
GWAS		Axial length ( 24144296) Refractive error ( 20835239)	Blood protein levels ( 30072576 28240269)
Interacting Genes		39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1	8 interacting genes: ABCG8 ACTC1 ACTN2 ATP6AP1 PTEN RNH1 TDGF1 TNFSF8
Entrez ID		70	283
HPRD ID		00015	00105
Ensembl ID		ENSG00000159251	ENSG00000214274
Uniprot IDs		B3KPP5 P68032	P03950 W0UV28
PDB IDs			1A4Y 1ANG 1AWZ 1B1E 1B1I 1B1J 1GV7 1H0D 1H52 1H53 1HBY 1K58 1K59 1K5A 1K5B 1UN3 1UN4 1UN5 2ANG 4AHD 4AHE 4AHF 4AHG 4AHH 4AHI 4AHJ 4AHK 4AHL 4AHM 4AHN 4AOH 4B36 5EOP 5EPZ 5EQO 5M9A 5M9C 5M9G 5M9J 5M9M 5M9P 5M9Q 5M9R 5M9S 5M9T 5M9V
Enriched GO Terms of Interacting Partners?
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