MLX and ZBTB32

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MLX	ZBTB32
Description		MAX dimerization protein MLX	zinc finger and BTB domain containing 32
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)
Interacting Genes		14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32	20 interacting genes: AR ATXN1 CAMK2B CFAP206 DAB1 E2F6 ELF2 ERVK-6 FANCC GATA2 HOXD4 MLX MVP PITX1 PRKAB2 RBPMS RHOXF2 TXNIP ZBTB16 ZNF490
Entrez ID		6945	27033
HPRD ID		04278	12055
Ensembl ID		ENSG00000108788	ENSG00000011590
Uniprot IDs		Q9UH92	Q9Y2Y4
PDB IDs			3M5B
Enriched GO Terms of Interacting Partners?
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