MLX and MXD4

Number of citations of the paper that reports this interaction (PubMedID 11230181)
37

Data Source:
HPRD (in vitro, in vivo)

		MLX	MXD4
Description		MAX dimerization protein MLX	MAX dimerization protein 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nuclear Chromatin
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity Protein Binding Protein Dimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression	Nuclear signaling by ERBB4
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)
Interacting Genes		14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32	6 interacting genes: MAX MLX SHBG SIN3A SMC3 TCP10L
Entrez ID		6945	10608
HPRD ID		04278	10103
Ensembl ID		ENSG00000108788	ENSG00000123933
Uniprot IDs		Q9UH92	Q14582
PDB IDs
Enriched GO Terms of Interacting Partners?
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