MLX and RBM39

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MLX	RBM39
Description		MAX dimerization protein MLX	RNA binding motif protein 39
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane	Nucleoplasm Microtubule Cytoskeleton Nuclear Speck Protein-containing Complex Centriolar Satellite
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity	RNA Binding Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	RNA Processing MRNA Processing RNA Splicing
Pathways		ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)	Blood protein levels ( 28240269)
Interacting Genes		14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32	51 interacting genes: AK8 APP ARL6IP4 BANP CHERP CLK1 CLK2 DDX39B ESR1 ESR2 FAM200A GOLGA2 H1-2 HNRNPH2 HOMEZ HSPB1 JUN KHDC4 KRTAP12-2 MCPH1 MLX MTNR1A NCOA6 NKAP NKAPD1 PGR PHC2 PPIG PRPF3 PRPF38A PRPF40A RBM23 RBM25 REL RNF113A RP9P SAP18 SAP30BP SDCBP SF3B4 SP100 SREK1IP1 SRPK1 SRPK2 SRSF11 THAP1 TOE1 TTC14 U2AF2 ZBTB22 ZCCHC10
Entrez ID		6945	9584
HPRD ID		04278	09201
Ensembl ID		ENSG00000108788	ENSG00000131051
Uniprot IDs		Q9UH92	A0A384NQ03 B4DRA0 E1P5S2 Q14498 Q6N037
PDB IDs			2JRS 2MHN 4OO6 4OZ0 4OZ1 4YUD 6Q0R 6Q0V 6Q0W
Enriched GO Terms of Interacting Partners?
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