ZBTB32 and MLX

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ZBTB32	MLX
Description		zinc finger and BTB domain containing 32	MAX dimerization protein MLX
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity Protein Binding Zinc Ion Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Protein Homodimerization Activity Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II
Pathways			ChREBP activates metabolic gene expression ChREBP activates metabolic gene expression
Drugs
Diseases
GWAS			Crohn's disease ( 21102463) Type 2 diabetes ( 30297969 29632382 30718926)
Interacting Genes		20 interacting genes: AR ATXN1 CAMK2B CFAP206 DAB1 E2F6 ELF2 ERVK-6 FANCC GATA2 HOXD4 MLX MVP PITX1 PRKAB2 RBPMS RHOXF2 TXNIP ZBTB16 ZNF490	14 interacting genes: APP GABARAPL2 ID3 LNX2 MAD1L1 MLXIP MLXIPL MNT MXD1 MXD4 RBM39 SAP30BP TLE5 ZBTB32
Entrez ID		27033	6945
HPRD ID		12055	04278
Ensembl ID		ENSG00000011590	ENSG00000108788
Uniprot IDs		Q9Y2Y4	Q9UH92
PDB IDs		3M5B
Enriched GO Terms of Interacting Partners?
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