TCEA2 and CCDC136

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		TCEA2	CCDC136
Description		transcription elongation factor A2	coiled-coil domain containing 136
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Elongation Factor Complex	Acrosomal Membrane Integral Component Of Membrane
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II	Acrosome Assembly Spermatogenesis Single Fertilization
Pathways
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)	Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)
Interacting Genes		50 interacting genes: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 KXD1 LMNA LRRK2 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26
Entrez ID		6919	64753
HPRD ID		16069	10887
Ensembl ID		ENSG00000171703	ENSG00000128596
Uniprot IDs		Q15560 Q6IB64	A0A024R758 Q96JN2
PDB IDs		2LW4
Enriched GO Terms of Interacting Partners?
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