CCDC136 and ABT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC136	ABT1
Description		coiled-coil domain containing 136	activator of basal transcription 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Integral Component Of Membrane	Nucleus Transcription Factor Complex Nucleolus
	Molecular Function		DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Small cell lung carcinoma ( 28604730) Waist circumference variance ( 31453325)
Interacting Genes		64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26	11 interacting genes: APP CCDC136 CDCA7L CEP70 EMD FAM9B LZTS2 PPP1CC PRNP SYNE4 TBP
Entrez ID		64753	29777
HPRD ID		10887	16469
Ensembl ID		ENSG00000128596	ENSG00000146109
Uniprot IDs		A0A024R758 Q96JN2	A0A024R029 Q9ULW3
PDB IDs
Enriched GO Terms of Interacting Partners?
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