TCEA2 and GTF2B

Number of citations of the paper that reports this interaction (PubMedID 8566795)
4

Data Source:
HPRD (two hybrid)

		TCEA2	GTF2B
Description		transcription elongation factor A2	general transcription factor IIB
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GO Annotations	Cellular Component	Transcription Elongation Factor Complex	Nucleus Nucleoplasm Transcription Factor TFIID Complex Chromosome Nuclear Body Protein-DNA Complex RNA Polymerase II Transcription Factor Complex Transcriptional Preinitiation Complex
	Molecular Function	DNA Binding Protein Binding Zinc Ion Binding	RNA Polymerase II Core Promoter Sequence-specific DNA Binding RNA Polymerase II Complex Binding Core Promoter Binding RNA Polymerase II Complex Recruiting Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding Zinc Ion Binding RNA Polymerase II General Transcription Initiation Factor Activity Acetyltransferase Activity TBP-class Protein Binding Thyroid Hormone Receptor Binding Promoter-specific Chromatin Binding
	Biological Process	DNA-templated Transcription, Elongation Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of Transcription By RNA Polymerase II	Transcriptional Start Site Selection At RNA Polymerase II Promoter DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Protein Acetylation Viral Process Histone Acetylation SnRNA Transcription By RNA Polymerase II Positive Regulation By Host Of Viral Transcription Positive Regulation Of Viral Transcription RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Core Promoter Binding RNA Polymerase II Core Complex Assembly
Pathways			HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome RNA Polymerase II Pre-transcription Events RNA polymerase II transcribes snRNA genes RNA polymerase II transcribes snRNA genes RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Adventurousness ( 30643258) Cerebrospinal AB1-42 levels in normal cognition ( 29274321) Pulse pressure ( 27841878 30578418) Serum thyroid-stimulating hormone levels ( 25436638) Systolic blood pressure ( 27841878) Triglyceride levels ( 29083408) Type 2 diabetes (adjusted for BMI) ( 30297969)	Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) Intraocular pressure ( 29617998) Obesity-related traits ( 23251661) Pulse pressure ( 30578418) Rosacea symptom severity ( 29771307) Systolic blood pressure ( 28135244 30578418)
Interacting Genes		50 interacting genes: ADAMTSL4 AKT1S1 ALAS1 APP BRCA1 CAMKV CCDC136 CCSER2 CDK11B CENPT CEP44 DAB1 DCAF10 DHRS2 DNAJB9 EAF2 EXOSC8 FAM9B FBF1 GOLGA2 GPKOW GRIPAP1 GTF2B KIAA1958 KRT40 KRTAP10-7 KRTAP5-9 KXD1 LMNA LRRK2 LZTS2 MAGEA11 MARK3 MCM2 MEOX2 MID2 MKRN3 RPA1 SH3GL2 TAX1BP1 TAX1BP3 TCF4 TFCP2 THAP1 TNIP1 TRAF2 TRIM27 TRIM54 TSGA10 WDR47	55 interacting genes: ATF4 BCL3 CIITA CREBBP CTBP1 DEPDC7 DHX9 DRAP1 EP300 ESR1 ESRRA FBXO25 FOXF2 GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 HMGCL HNF4A HSF1 IKZF1 JAK3 JUN KLF5 MCM2 MECP2 NCOA1 NCOA3 NCOA4 NCOR1 NOLC1 NR1D2 NR2F1 NR5A1 POLR2A POLR2E POU3F2 PSMC2 PSMC5 REL RELA REST SLC22A2 SRA1 TAF11 TAF9 TBP TBPL1 TCEA2 THRA TNIP1 TRAM2 VDR YWHAE
Entrez ID		6919	2959
HPRD ID		16069	08928
Ensembl ID		ENSG00000171703	ENSG00000137947
Uniprot IDs		Q15560 Q6IB64	Q00403
PDB IDs		2LW4	1C9B 1DL6 1RLY 1RO4 1TFB 1VOL 2PHG 5IY6 5IY7 5IY8 5IY9 5IYA 5IYB 5IYC 5IYD 5WH1 6O9L
Enriched GO Terms of Interacting Partners?
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