CCDC136 and CDK2AP1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CCDC136	CDK2AP1
Description		coiled-coil domain containing 136	cyclin dependent kinase 2 associated protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Membrane Integral Component Of Membrane	Nucleus Nucleoplasm Cytosol Perinuclear Region Of Cytoplasm
	Molecular Function		Protein Binding DNA Polymerase Binding
	Biological Process	Acrosome Assembly Spermatogenesis Single Fertilization	Positive Regulation Of Protein Phosphorylation DNA-dependent DNA Replication Cell Cycle
Pathways
Drugs
Diseases
GWAS		Reading disability or specific language impairment (pleiotropy) ( 25065397) Reading disability or specific language impairment adjusted for intelligence quotient (pleiotropy) ( 25065397)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Allergic rhinitis ( 30013184) Allergy ( 27182965) Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 30072576) Heel bone mineral density ( 30598549) Intelligence (MTAG) ( 29326435) Schizophrenia ( 25056061 29483656 23974872) Total cholesterol levels ( 29615537) Tourette syndrome ( 30818990)
Interacting Genes		64 interacting genes: ABT1 AQP1 ATP5PO ATXN1 BARD1 BLOC1S6 BYSL C1orf216 CBX8 CCDC146 CCHCR1 CDC5L CDK2AP1 CEP57L1 COIL CWF19L2 DISC1 ENKD1 FAM107A FAM161A GFI1B HAUS1 HDAC4 HGS HMG20A HMG20B JMY KANSL1 KAT5 KIFC3 LENG1 MAGEB4 MOS NDN NEBL PDLIM5 PKN2 PPP1R18 PRPF31 PSMD9 RAB33A SHFL SMARCE1 TBRG1 TCEA2 TNNT1 TXLNA UBQLN4 USP2 WT1 ZBTB38 ZC2HC1C ZNF20 ZNF230 ZNF250 ZNF408 ZNF417 ZNF490 ZNF564 ZNF572 ZNF581 ZNF587 ZNF688 ZSCAN26	6 interacting genes: CCDC136 CDK2 CDK2AP2 MRFAP1L1 POLA1 ZNF420
Entrez ID		64753	8099
HPRD ID		10887	03726
Ensembl ID		ENSG00000128596	ENSG00000111328
Uniprot IDs		A0A024R758 Q96JN2	O14519
PDB IDs			2KW6
Enriched GO Terms of Interacting Partners?
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