TAF12 and NFYA

Number of citations of the paper that reports this interaction (PubMedID 11689552)
22

Data Source:
BioGRID (pull down)

		TAF12	NFYA
Description		TATA-box binding protein associated factor 12	nuclear transcription factor Y subunit alpha
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex	Nuclear Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Factor Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)	White blood cell count ( 27863252)
Interacting Genes		23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	42 interacting genes: APP APPBP2 ATF6 ATF6B BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NEU1 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 PWP1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 USF1 USF2 ZC3H10 ZHX1 ZHX2 ZHX3
Entrez ID		6883	4800
HPRD ID		15981	01793
Ensembl ID		ENSG00000120656	ENSG00000001167
Uniprot IDs		Q16514	A0A024RD22 P23511
PDB IDs		1H3O 6MZC 6MZD 6MZL 6MZM	4AWL 6QMP
Enriched GO Terms of Interacting Partners?
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