NFYA and ELF1

Number of citations of the paper that reports this interaction (PubMedID 9668064)
15

Data Source:
BioGRID (pull down)

		NFYA	ELF1
Description		nuclear transcription factor Y subunit alpha	E74 like ETS transcription factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex RNA Polymerase II Transcription Factor Complex	Nuclear Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA-binding Transcription Factor Activity Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription By RNA Polymerase II Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Iron Regulation Of Cholesterol Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Rhythmic Process	Regulation Of Cytokine Production Regulation Of Cytokine-mediated Signaling Pathway Regulation Of Transcription By RNA Polymerase II Cell Differentiation Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Regulation Of B Cell Receptor Signaling Pathway Negative Regulation Of T Cell Receptor Signaling Pathway
Pathways		PPARA activates gene expression Activation of gene expression by SREBF (SREBP) Activation of gene expression by SREBF (SREBP) ATF4 activates genes in response to endoplasmic reticulum stress ATF6 (ATF6-alpha) activates chaperone genes ATF6 (ATF6-alpha) activates chaperone genes FOXO-mediated transcription of cell death genes	RUNX1 regulates transcription of genes involved in BCR signaling RUNX1 regulates transcription of genes involved in interleukin signaling
Drugs
Diseases
GWAS		White blood cell count ( 27863252)	Cervical cancer ( 28806749) Crohn's disease ( 23266558) Height ( 31562340) Lymphocyte counts ( 27863252) Lymphocyte percentage of white cells ( 27863252) Neutrophil percentage of white cells ( 27863252) Systemic lupus erythematosus ( 27399966 23273568 21044949) Total cholesterol levels ( 30275531)
Interacting Genes		42 interacting genes: APP APPBP2 ATF6 ATF6B BRCA1 CCNA2 CDC25A CDK2 CDKN1A CEBPA CSNK2A1 E2F6 ELF1 GTF2A1 HMGA1 JUN KPNB1 LUC7L2 NEU1 NFYB NFYC NR5A1 PAPOLG POGZ POU2F1 PWP1 SP1 SPI1 SREBF2 SRF SRSF1 TAF11 TAF12 TAF6 TCAF1 TP53 USF1 USF2 ZC3H10 ZHX1 ZHX2 ZHX3	9 interacting genes: HMGA1 HOXC13 NFKB1 NFYA NFYB RB1 REL RUNX1 SP1
Entrez ID		4800	1997
HPRD ID		01793	01808
Ensembl ID		ENSG00000001167	ENSG00000120690
Uniprot IDs		A0A024RD22 P23511	A0A024RDU6 P32519 Q6MZZ4
PDB IDs		4AWL 6QMP
Enriched GO Terms of Interacting Partners?
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