TAF12 and TAF10

Number of citations of the paper that reports this interaction (PubMedID 7729427)
44

Data Source:
HPRD (in vivo, in vitro)

		TAF12	TAF10
Description		TATA-box binding protein associated factor 12	TATA-box binding protein associated factor 10
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GO Annotations	Cellular Component	SAGA Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex STAGA Complex Transcription Factor TFTC Complex SLIK (SAGA-like) Complex	PCAF Complex Nucleus Nucleoplasm Transcription Factor TFIID Complex Cytoplasm STAGA Complex Transcription Factor TFTC Complex Perinuclear Region Of Cytoplasm
	Molecular Function	DNA Binding Transcription Coactivator Activity Histone Acetyltransferase Activity Protein Binding Transcription Factor Binding RNA Polymerase II General Transcription Initiation Factor Activity TBP-class Protein Binding Protein Heterodimerization Activity	DNA Binding Histone Acetyltransferase Activity Protein Binding RNA Polymerase II General Transcription Initiation Factor Activity Enzyme Binding Estrogen Receptor Binding Identical Protein Binding RNA Polymerase Binding Promoter-specific Chromatin Binding
	Biological Process	DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Histone H3 Acetylation Positive Regulation Of DNA-binding Transcription Factor Activity RNA Polymerase II Preinitiation Complex Assembly Regulation Of Signal Transduction By P53 Class Mediator Positive Regulation Of Nucleic Acid-templated Transcription	G1/S Transition Of Mitotic Cell Cycle DNA-templated Transcription, Initiation Transcription By RNA Polymerase II Transcription Initiation From RNA Polymerase II Promoter Apoptotic Process Regulation Of Gene Expression Histone Deubiquitination Protein Deubiquitination Cellular Protein-containing Complex Assembly Multicellular Organism Growth Histone H3 Acetylation Regulation Of DNA Binding Hepatocyte Differentiation Regulation Of Signal Transduction By P53 Class Mediator
Pathways		HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance	HIV Transcription Initiation RNA Polymerase II HIV Promoter Escape Transcription of the HIV genome HATs acetylate histones Ub-specific processing proteases RNA Polymerase II Pre-transcription Events Regulation of TP53 Activity through Phosphorylation RNA Polymerase II Promoter Escape RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase II Transcription Initiation RNA Polymerase II Transcription Initiation And Promoter Clearance
Drugs
Diseases
GWAS		Type 2 diabetes ( 31049640)
Interacting Genes		23 interacting genes: ATF7 CPSF1 H3-4 MYC NFYA NFYB NFYC PRKAR2B TAF1 TAF10 TAF11 TAF15 TAF1A TAF2 TAF4 TAF4B TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I	23 interacting genes: ATXN7 ESR1 FANCA FTL H3-4 POLR2A PSMC5 SETD7 SUPT7L TAF1 TAF11 TAF12 TAF13 TAF2 TAF3 TAF4 TAF5 TAF6 TAF7 TAF8 TAF9 TBP UBE2I
Entrez ID		6883	6881
HPRD ID		15981	15972
Ensembl ID		ENSG00000120656	ENSG00000166337
Uniprot IDs		Q16514	Q12962
PDB IDs		1H3O 6MZC 6MZD 6MZL 6MZM	2F69 3M53 3M54 3M55 3M56 3M57 3M58 3M59 3M5A 4J7F 4J7I 4J83 4J8O 4WV4 5EG2 6MZC 6MZD 6MZL 6MZM
Enriched GO Terms of Interacting Partners?
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