BSG and CRBN

Number of citations of the paper that reports this interaction (PubMedID 27294876)
28

Data Source:
BioGRID (pull down, pull down)

		BSG	CRBN
Description		basigin (Ok blood group)	cereblon
Image
GO Annotations	Cellular Component	Golgi Membrane Acrosomal Membrane Mitochondrion Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Axon Sarcolemma Melanosome Intracellular Membrane-bounded Organelle Membrane Raft Extracellular Exosome	Nucleus Cytoplasm Membrane Cul4A-RING E3 Ubiquitin Ligase Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Mannose Binding Cadherin Binding Cell-cell Adhesion Mediator Activity	Protein Binding Ion Channel Binding Metal Ion Binding
	Biological Process	Pyruvate Metabolic Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Cell Surface Receptor Signaling Pathway Axon Guidance Embryo Implantation Extracellular Matrix Disassembly Extracellular Matrix Organization Odontogenesis Of Dentin-containing Tooth Response To Peptide Hormone Response To Mercury Ion Decidualization Leukocyte Migration Response To CAMP Dendrite Self-avoidance Protein Localization To Plasma Membrane	Protein Ubiquitination Negative Regulation Of Protein Complex Assembly Positive Regulation Of Protein Complex Assembly Negative Regulation Of Ion Transmembrane Transport Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Pathways		Degradation of the extracellular matrix Basigin interactions Integrin cell surface interactions Proton-coupled monocarboxylate transport Defective SLC16A1 causes symptomatic deficiency in lactate transport (SDLT) Pyruvate metabolism
Drugs			Lenalidomide Thalidomide Pomalidomide
Diseases			Nonsyndromic autosomal recessive mental retardation (NS-ARMR)
GWAS		Alzheimer's disease (late onset) ( 28714976)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Basophil percentage of granulocytes ( 27863252) Basophil percentage of white cells ( 27863252) Immune response to smallpox vaccine (IL-6) ( 22542470) Knee osteoarthritis ( 27696742) Restless legs syndrome ( 29029846) White blood cell count (basophil) ( 29403010 27863252) White matter integrity ( 23218918)
Interacting Genes		12 interacting genes: CAV1 CRBN HGS MMP1 PDLIM7 PPIA PPIL2 PPP2R1B SLC16A1 SLC16A3 SLC2A4 UBC	33 interacting genes: APPL2 BCL6 BCL6B BSG CSNK1A1 EGR1 EGR4 GLUL GRB2 GSPT1 GZF1 HIC1 HIC2 IKZF3 KDM1A OSR1 OSR2 PAK5 PIK3R3 RBPMS RBX1 SALL1 SALL3 SALL4 SLC16A1 SQSTM1 SUV39H1 TP53 UBE2D1 WIZ ZBTB7A ZBTB7B ZFP91
Entrez ID		682	51185
HPRD ID		00176	16750
Ensembl ID		ENSG00000172270	ENSG00000113851
Uniprot IDs		P35613 Q54A51	Q96SW2
PDB IDs		3B5H 3I84 3I85 3QQN 3QR2 4U0Q 5X0T 5XF0	4M91 4TZ4 5FQD 5HXB 5V3O 6BN7 6BN8 6BN9 6BNB 6BOY 6H0F 6H0G
Enriched GO Terms of Interacting Partners?
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