KIFC3 and TSG101

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		KIFC3	TSG101
Description		kinesin family member C3	tumor susceptibility 101
Image
GO Annotations	Cellular Component	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Exosome	ESCRT I Complex Nucleolus Cytoplasm Endosome Early Endosome Late Endosome Multivesicular Body Microtubule Organizing Center Cytosol Plasma Membrane Endosome Membrane Early Endosome Membrane Late Endosome Membrane Host Cell Extracellular Exosome Flemming Body
	Molecular Function	Microtubule Motor Activity Protein Binding ATP Binding Microtubule Binding ATP-dependent Microtubule Motor Activity, Minus-end-directed ATPase Activity	DNA Binding Transcription Corepressor Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity Ubiquitin Protein Ligase Binding Protein Homodimerization Activity Ubiquitin Binding Protein-containing Complex Binding Virion Binding Calcium-dependent Protein Binding
	Biological Process	Microtubule-based Movement Golgi Organization Visual Perception Zonula Adherens Maintenance Epithelial Cell-cell Adhesion	Regulation Of Cell Growth Protein Monoubiquitination Extracellular Transport Cell Cycle Arrest Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Cell Proliferation Endosome To Lysosome Transport Protein Transport Endosomal Transport Macroautophagy Viral Life Cycle Keratinocyte Differentiation Multivesicular Body Assembly Viral Budding Via Host ESCRT Complex Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Viral Budding Cell Division Intracellular Transport Of Virus Autophagosome Maturation Regulation Of Viral Release From Host Cell Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Exosomal Secretion Regulation Of Extracellular Exosome Assembly Positive Regulation Of Viral Budding Via Host ESCRT Complex Exosomal Secretion Positive Regulation Of Ubiquitin-dependent Endocytosis
Pathways			Budding and maturation of HIV virion Membrane binding and targetting of GAG proteins Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events Late endosomal microautophagy
Drugs
Diseases
GWAS
Interacting Genes		93 interacting genes: ABI2 ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CBY2 CCDC102B CCDC136 CCDC28A CCDC33 CDK18 CDR2 CEP55 CEP57L1 CLIP4 COG7 CREB5 CYTH4 DCTN2 DCX DEUP1 DTNBP1 ESRRG FAM124A FANCL FBXO7 FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SVIL SYCE1 TCEANC TLE5 TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655 ZNF688	88 interacting genes: AATF ADRB2 AKAP9 AR ARRDC1 BCAS3 BCR BIRC2 CCND3 CDKN1A CDKN2D CDS2 CEP55 CNOT7 DAXX DMAP1 DMRTB1 DNMT1 DZIP3 EP300 FAM9B GGA1 GGA3 GMCL1 HAUS1 HCK HGS IQGAP1 ITSN1 JUN KIF5A KIFC3 KLK5 KLK6 KRT13 KRT15 KRT31 LRSAM1 MDM2 MGRN1 MKRN3 MTA3 NR3C1 PDCD6IP PDLIM7 PIAS1 PPFIBP2 PRSS50 QKI RAD18 RASL10B RBPMS RNF111 RNF126 RNF41 ROCK1 SCAMP3 SCGB3A1 SCNN1A SH3GLB2 SNF8 SNX32 STK11 SYCE1 TAX1BP1 TEX11 TFF1 THRB THRSP TNIP2 TNNT3 TOM1L1 TP53 TRAIP TRIM23 TRIM35 TRIM46 TRIM74 UBA52 UBC USHBP1 VPS11 VPS28 VPS36 VPS37A VPS37B VPS37C VPS37D
Entrez ID		3801	7251
HPRD ID		05171	03229
Ensembl ID		ENSG00000140859	ENSG00000074319
Uniprot IDs		B7Z5U4 B7Z808 B7Z896 F5H3M2 Q9BVG8	Q99816
PDB IDs		5WDE	1KPP 1KPQ 1M4P 1M4Q 1S1Q 2F0R 3IV1 3OBQ 3OBS 3OBU 3OBX 3P9G 3P9H 4EJE 4YC1 4ZNY 5VKG
Enriched GO Terms of Interacting Partners?
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