EXOC7 and ARFGEF2

Number of citations of the paper that reports this interaction (PubMedID 15705715)
19

Data Source:
HPRD (two hybrid)

		EXOC7	ARFGEF2
Description		exocyst complex component 7	ADP ribosylation factor guanine nucleotide exchange factor 2
Image		No pdb structure
GO Annotations	Cellular Component	Exocyst Microtubule Organizing Center Cytosol Plasma Membrane Membrane Growth Cone Membrane Centriolar Satellite Flemming Body	Golgi Membrane Trans-Golgi Network Microtubule Organizing Center Cytosol Axonemal Microtubule Membrane Cell Junction Cytoplasmic Vesicle Asymmetric Synapse Symmetric Synapse Dendritic Spine Perinuclear Region Of Cytoplasm Recycling Endosome
	Molecular Function	Protein Binding	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Myosin Binding Protein Kinase A Regulatory Subunit Binding GABA Receptor Binding
	Biological Process	Exocytosis Protein Transport Regulation Of Macroautophagy Regulation Of Entry Of Bacterium Into Host Cell	Receptor Recycling Exocytosis Golgi To Plasma Membrane Transport Endosome Organization Endomembrane System Organization Protein Transport Regulation Of ARF Protein Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Intracellular Signal Transduction
Pathways		Translocation of SLC2A4 (GLUT4) to the plasma membrane Insulin processing VxPx cargo-targeting to cilium	Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases			Periventricular nodular heterotopia (PVNH)
GWAS			Anger ( 24489884) Birth weight ( 31043758) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Height ( 28552196) Intelligence (MTAG) ( 29326435) Loneliness ( 29970889) Loneliness (MTAG) ( 29970889) Offspring birth weight ( 31043758) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in non-smokers ( 28443625)
Interacting Genes		25 interacting genes: AKTIP ARFGEF2 ARPC1A BBS1 BBS2 BBS4 CCDC85B CDC5L DISC1 DLG3 EXOC2 EXOC4 GRIN2B HGS IFT20 KXD1 PRPF19 RALA RHOQ RTN4IP1 SMARCE1 SSC5D TRAF4 USHBP1 ZC3H14	9 interacting genes: ARFGEF1 EXOC7 GABRB1 GABRB2 GABRB3 PNPLA2 PRKAR1A PRKAR2A PRPF40A
Entrez ID		23265	10564
HPRD ID		16292	09250
Ensembl ID		ENSG00000182473	ENSG00000124198
Uniprot IDs		B4DJ07 B5MCY9 Q63HP7 Q9UPT5	Q59FR3 Q86TH5 Q9Y6D5
PDB IDs			3L8N 3SWV
Enriched GO Terms of Interacting Partners?
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