BMX and CLNK

Number of citations of the paper that reports this interaction (PubMedID 25814554)
22

Data Source:
BioGRID (two hybrid)

		BMX	CLNK
Description		BMX non-receptor tyrosine kinase	cytokine dependent hematopoietic cell linker
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Ruffle Membrane	Cytoplasm Protein-containing Complex
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	SH3/SH2 Adaptor Activity Protein Binding Protein-containing Complex Binding
	Biological Process	Protein Phosphorylation Phosphatidylinositol Biosynthetic Process Apoptotic Process Cell Adhesion Signal Transduction Mesoderm Development Peptidyl-tyrosine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation	Positive Regulation Of Natural Killer Cell Cytokine Production Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Cell Death Negative Regulation Of Natural Killer Cell Activation Intracellular Signal Transduction
Pathways		Apoptotic cleavage of cellular proteins Synthesis of PIPs at the plasma membrane
Drugs
Diseases
GWAS			Alzheimer's disease or family history of Alzheimer's disease ( 30617256) Family history of Alzheimer's disease ( 30617256) Resistance to antihypertensive treatment in hypertension ( 28222112) Rheumatoid arthritis ( 30423114 24390342) Systemic lupus erythematosus ( 28714469) Takayasu arteritis ( 25604533) Urate levels ( 31578528) Uterine fibroid size (maximum dimension) ( 30196971) Vitiligo ( 22561518)
Interacting Genes		25 interacting genes: APP BCAR1 BTK C12orf45 CASP3 CAV1 CLNK EGFR ERBB2 FBXO25 ITK KDR PAK1 PTK2 PTPN21 PTPRD RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B	30 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD JAKMIP1 LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX
Entrez ID		660	116449
HPRD ID		02111	14720
Ensembl ID		ENSG00000102010	ENSG00000109684
Uniprot IDs		P51813	Q7Z7G1
PDB IDs		2EKX 2YS2 3SXR 3SXS
Enriched GO Terms of Interacting Partners?
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