CLNK and WWOX

  • Number of citations of the paper that reports this interaction (PubMedID 25814554)
  • 22
  • Data Source:
  • BioGRID (two hybrid)

CLNK

WWOX

Description cytokine dependent hematopoietic cell linker WW domain containing oxidoreductase
Image No pdb structure
GO Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Alzheimer's disease or family history of Alzheimer's disease ( 30617256)
  • Family history of Alzheimer's disease ( 30617256)
  • Resistance to antihypertensive treatment in hypertension ( 28222112)
  • Rheumatoid arthritis ( 30423114 24390342)
  • Systemic lupus erythematosus ( 28714469)
  • Takayasu arteritis ( 25604533)
  • Urate levels ( 31578528)
  • Uterine fibroid size (maximum dimension) ( 30196971)
  • Vitiligo ( 22561518)
  • Acute graft versus host disease in bone marrow transplantation (recipient effect) ( 27595289)
  • Alzheimer's disease (late onset) ( 30820047)
  • Anorexia nervosa ( 23568457)
  • Bipolar disorder (body mass index interaction) ( 24322204)
  • Brain volume in infants (white matter) ( 28763065)
  • Cardiac structure and function ( 19584346)
  • Clozapine-induced cytotoxicity ( 25656473)
  • Colorectal cancer ( 30529582 29228715)
  • Daytime sleep phenotypes ( 27126917)
  • Diffusing capacity of carbon monoxide ( 30694715)
  • Early-onset Parkinson's disease ( 28256260)
  • Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678)
  • Familial squamous cell lung carcinoma ( 29924316)
  • FEV1 ( 30804560)
  • Hip shape (DXA scan) ( 30320955)
  • Idiopathic dilated cardiomyopathy ( 29495422)
  • Lung function (forced vital capacity) ( 24929828)
  • Lung function (FVC) ( 30804560)
  • Macular thickness ( 30535121)
  • Metabolite levels ( 23823483)
  • Metabolite levels (5-HIAA) ( 23319000)
  • Molybdenum levels ( 26025379)
  • Multiple sclerosis ( 31604244 24076602)
  • Obesity ( 21552555)
  • Paclitaxel disposition in epithelial ovarian cancer ( 29367611)
  • Peak expiratory flow ( 30804560)
  • Peripheral arterial disease (traffic-related air pollution interaction) ( 27082954)
  • Post bronchodilator FEV1/FVC ratio ( 26634245)
  • Pulmonary function ( 21946350)
  • Pulmonary function (smoking interaction) ( 23284291)
  • Radiation response ( 20923822)
  • Response to amphetamines ( 22952603)
  • Response to antipsychotic treatment in schizophrenia (reasoning) ( 21107309)
  • Response to fenofibrate (HDL cholesterol levels) ( 27002377)
  • Serum thyroid-stimulating hormone levels ( 25436638)
  • Serum uric acid levels in response to allopurinol in gout ( 25676789)
  • Stress sensitivity (neuroticism score x major depressive disorder status interaction) ( 30571770)
  • Systemic juvenile idiopathic arthritis ( 27927641)
  • Type 2 diabetes ( 22158537)
  • Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes 30 interacting genes: ANKRD50 ARAP3 BMX COQ9 CRK CYB561D2 EGFR ERBB2 FAM217A GLIS3 GRB2 GSTCD JAKMIP1 LCP2 NME4 P4HA2 PACSIN3 PIK3R1 PIK3R3 PPP1R7 PTK7 RASSF1 RB1 RPAIN SFMBT1 SMARCD1 SOCS6 STK36 TXK WWOX 25 interacting genes: APBB2 CLNK CPSF2 CPSF7 ERBB4 EZR FIP1L1 HNRNPK HYAL2 LATS1 MAPK8 NUDT21 SCAMP3 SEC23IP SF3B3 SMAD4 SRC TCERG1 TFAP2C TNK2 TP53 TP73 UBB WDR33 WIPF2
Entrez ID 116449 51741
HPRD ID 14720 05501
Ensembl ID ENSG00000109684 ENSG00000186153
Uniprot IDs Q7Z7G1 A0A411HBC7 Q9NZC7
PDB IDs 1WMV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?