BMX and TEC

Number of citations of the paper that reports this interaction (PubMedID 12573241)
13

Data Source:
HPRD (in vitro)

		BMX	TEC
Description		BMX non-receptor tyrosine kinase	tec protein tyrosine kinase
Image
GO Annotations	Cellular Component	Nucleoplasm Cytosol Plasma Membrane Ruffle Membrane	Cytosol Cytoskeleton Plasma Membrane
	Molecular Function	Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Metal Ion Binding	Non-membrane Spanning Protein Tyrosine Kinase Activity Protein Binding ATP Binding Phospholipid Binding Metal Ion Binding
	Biological Process	Protein Phosphorylation Phosphatidylinositol Biosynthetic Process Apoptotic Process Cell Adhesion Signal Transduction Mesoderm Development Peptidyl-tyrosine Phosphorylation Intracellular Signal Transduction Protein Autophosphorylation	Adaptive Immune Response Protein Phosphorylation Integrin-mediated Signaling Pathway Regulation Of Platelet Activation Peptidyl-tyrosine Phosphorylation Cytokine-mediated Signaling Pathway Intracellular Signal Transduction Peptidyl-tyrosine Autophosphorylation Fc-epsilon Receptor Signaling Pathway Tissue Regeneration Positive Regulation Of Peptidyl-tyrosine Phosphorylation T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway
Pathways		Apoptotic cleavage of cellular proteins Synthesis of PIPs at the plasma membrane	Signaling by SCF-KIT FCERI mediated Ca+2 mobilization FCERI mediated Ca+2 mobilization Interleukin-3, Interleukin-5 and GM-CSF signaling
Drugs
Diseases
GWAS			Crohn's disease ( 23128233) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Rheumatoid arthritis ( 30423114 24390342) Systolic blood pressure ( 27841878)
Interacting Genes		25 interacting genes: APP BCAR1 BTK C12orf45 CASP3 CAV1 CLNK EGFR ERBB2 FBXO25 ITK KDR PAK1 PTK2 PTPN21 PTPRD RAP1A RUFY1 RUFY2 SRC STAT1 STAT3 STAT5A TEC TNFRSF1B	31 interacting genes: ARHGEF12 BMX BTK DOK1 ERBB2 FASLG FBXO7 GNA12 IKBKG JAK1 JAK2 KIT LRRK1 LYN PIK3R1 PIK3R2 PIK3R3 PIP4K2A PIP5K1A PLCG1 PLCG2 PLK4 PRLR PTPN18 PTPN21 SHC1 SOCS1 STAP1 TP53 VAV1 WAS
Entrez ID		660	7006
HPRD ID		02111	02786
Ensembl ID		ENSG00000102010	ENSG00000135605
Uniprot IDs		P51813	P42680
PDB IDs		2EKX 2YS2 3SXR 3SXS	2LUL
Enriched GO Terms of Interacting Partners?
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