PCBD1 and ACIN1

Number of citations of the paper that reports this interaction (PubMedID 20195357)
30

Data Source:
BioGRID (pull down)

		PCBD1	ACIN1
Description		pterin-4 alpha-carbinolamine dehydratase 1	apoptotic chromatin condensation inducer 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Cytosol Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytosol Plasma Membrane Nuclear Speck ASAP Complex
	Molecular Function	Transcription Coactivator Activity Phenylalanine 4-monooxygenase Activity Protein Binding 4-alpha-hydroxytetrahydrobiopterin Dehydratase Activity Identical Protein Binding	Nucleic Acid Binding RNA Binding Protein Binding ATPase Activity Enzyme Binding
	Biological Process	L-phenylalanine Catabolic Process Tetrahydrobiopterin Biosynthetic Process Regulation Of Protein Binding Positive Regulation Of Transcription, DNA-templated Oxidation-reduction Process	MRNA Processing RNA Splicing Erythrocyte Differentiation Apoptotic Chromosome Condensation Positive Regulation Of Monocyte Differentiation
Pathways		Phenylalanine metabolism	Apoptotic cleavage of cellular proteins
Drugs		L-erythro-7,8-dihydrobiopterin
Diseases		Phenylketonuria (PKU); Hyperphenylalaninemia, BH4-deficient
GWAS		Blood protein levels ( 30072576) Chronotype ( 30696823) Immature fraction of reticulocytes ( 27863252) Microalbuminuria ( 26631737) Obesity-related traits ( 23251661)
Interacting Genes		49 interacting genes: ACIN1 APP BRD7 CACNA1C CALCOCO1 CDK5RAP2 CEBPZ DENND4A DIP2C DVL2 DYRK1B EHMT1 FXR2 GORASP2 GTF3C3 HES4 HNF1A HNF4A KLF13 LNX1 MIS18BP1 NFKB1 NIF3L1 NTAQ1 NUDT18 PAH PAPOLG PCBD2 POLR3A RBL2 RPS24 SAP30 SCMH1 SMARCD1 SOWAHC SUPT5H TFF3 TIMELESS TRIM5 WWP1 ZBTB25 ZNF195 ZNF202 ZNF23 ZNF263 ZNF451 ZNF567 ZNF688 ZNF714	10 interacting genes: ABCF3 AKR1C3 BTBD10 CASP3 CSNK2A1 KLHL26 PAFAH1B2 PCBD1 SRPK2 YWHAG
Entrez ID		5092	22985
HPRD ID		00523	05191
Ensembl ID		ENSG00000166228	ENSG00000100813
Uniprot IDs		P61457	B4DQZ7 Q9UKV3
PDB IDs			6G6S
Enriched GO Terms of Interacting Partners?
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