CREB3L2 and GAS7

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CREB3L2	GAS7
Description		cAMP responsive element binding protein 3 like 2	growth arrest specific 7
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum	Cytoplasm Cytoskeleton Plasma Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding Transcription Regulatory Region DNA Binding	DNA-binding Transcription Factor Activity Protein Binding Cytoskeletal Protein Binding
	Biological Process	Chondrocyte Differentiation ER To Golgi Vesicle-mediated Transport Response To Wounding Positive Regulation Of Neuron Projection Development Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development	Regulation Of Transcription, DNA-templated Cell Cycle Arrest Neuron Differentiation Neuron Projection Morphogenesis
Pathways		CREB3 factors activate genes
Drugs
Diseases
GWAS		Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Total cholesterol levels ( 31217584)	Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glaucoma ( 30104761 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)
Interacting Genes		9 interacting genes: CEP19 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 ZNF212	20 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 NCKAP1 NCKAP1L NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2
Entrez ID		64764	8522
HPRD ID		16391	16011
Ensembl ID		ENSG00000182158	ENSG00000007237
Uniprot IDs		Q68D60 Q70SY1	O60861
PDB IDs			2LX7 2YSH
Enriched GO Terms of Interacting Partners?
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