GAS7 and PACSIN1

Number of citations of the paper that reports this interaction (PubMedID 20936779)
85

Data Source:
BioGRID (two hybrid)

		GAS7	PACSIN1
Description		growth arrest specific 7	protein kinase C and casein kinase substrate in neurons 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane	Cytoplasm Endosome Cytosol Cytoskeleton Plasma Membrane Cell Junction COPI-coated Vesicle Cytoplasmic Vesicle Membrane Ruffle Membrane Axon Terminus Synapse Perinuclear Region Of Cytoplasm Photoreceptor Ribbon Synapse Presynaptic Endocytic Zone
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Cytoskeletal Protein Binding	Protein Binding Phospholipid Binding Cytoskeletal Protein Binding Identical Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Cell Cycle Arrest Neuron Differentiation Neuron Projection Morphogenesis	Cytoskeleton Organization Actin Filament Organization Regulation Of Endocytosis Negative Regulation Of Endocytosis Synaptic Vesicle Endocytosis Neuron Projection Morphogenesis Protein Localization To Membrane Protein Localization To Plasma Membrane Plasma Membrane Tubulation Positive Regulation Of Dendrite Development
Pathways			Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glaucoma ( 30104761 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body mass index ( 29273807 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index in physically active individuals ( 28448500) Free thyroxine concentration ( 30367059) High density lipoprotein cholesterol levels ( 30498476) Inflammatory bowel disease ( 27569725) Waist-to-hip ratio adjusted for BMI ( 28552196)
Interacting Genes		20 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 NCKAP1 NCKAP1L NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2	24 interacting genes: ANKRD24 ARHGAP17 DNM1 EHBP1 FTH1 GAS7 HTT ITCH JADE2 KAT7 KHDRBS1 MAPT MT-ATP8 PACSIN2 PACSIN3 POT1 RTKN2 SOS1 SPTBN1 SYNJ1 TPM4 TRPV4 WASF2 WASL
Entrez ID		8522	29993
HPRD ID		16011	05936
Ensembl ID		ENSG00000007237	ENSG00000124507
Uniprot IDs		O60861	Q5TZC3 Q9BY11
PDB IDs		2LX7 2YSH	3HAH 3HAI 3Q84 3QNI
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?