CREB3L2 and GCFC2

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		CREB3L2	GCFC2
Description		cAMP responsive element binding protein 3 like 2	GC-rich sequence DNA-binding factor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Perinuclear Endoplasmic Reticulum	Nucleus Nucleoplasm Nucleolus Cytosol U2-type Post-mRNA Release Spliceosomal Complex
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific CAMP Response Element Binding Transcription Regulatory Region DNA Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Protein Binding
	Biological Process	Chondrocyte Differentiation ER To Golgi Vesicle-mediated Transport Response To Wounding Positive Regulation Of Neuron Projection Development Endoplasmic Reticulum Unfolded Protein Response Response To Endoplasmic Reticulum Stress Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Cartilage Development	Negative Regulation Of Transcription By RNA Polymerase II Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription, DNA-templated
Pathways		CREB3 factors activate genes	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body fat distribution (trunk fat ratio) ( 30664634) Height ( 31562340) LDL cholesterol levels ( 30698716) LDL cholesterol levels in current drinkers ( 30698716) LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) Metabolite levels ( 23823483) Pulse pressure ( 27841878) Total cholesterol levels ( 31217584)	Chronotype ( 30696823) Hippocampal atrophy ( 22745009)
Interacting Genes		9 interacting genes: CEP19 GAS7 GCFC2 GULP1 PTP4A1 PXN RGS16 RND1 ZNF212	2 interacting genes: ATXN1 CREB3L2
Entrez ID		64764	6936
HPRD ID		16391	01791
Ensembl ID		ENSG00000182158	ENSG00000005436
Uniprot IDs		Q68D60 Q70SY1	A4UHR0 B3KUM5 P16383 Q9BVX3
PDB IDs
Enriched GO Terms of Interacting Partners?
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