GAS7 and FMNL1

Number of citations of the paper that reports this interaction (PubMedID 16055720)
81

Data Source:
BioGRID (pull down)

		GAS7	FMNL1
Description		growth arrest specific 7	formin like 1
Image
GO Annotations	Cellular Component	Cytoplasm Cytoskeleton Plasma Membrane	Cytosol Plasma Membrane Cell Cortex Membrane Bleb Phagocytic Vesicle Extracellular Exosome
	Molecular Function	DNA-binding Transcription Factor Activity Protein Binding Cytoskeletal Protein Binding	Molecular_function Protein Binding Profilin Binding GTPase Activating Protein Binding Rac GTPase Binding Actin Filament Binding
	Biological Process	Regulation Of Transcription, DNA-templated Cell Cycle Arrest Neuron Differentiation Neuron Projection Morphogenesis	Substrate-dependent Cell Migration Regulation Of Cell Shape Cell Migration Cortical Actin Cytoskeleton Organization Actin Filament Severing
Pathways			RHO GTPases Activate Formins RHO GTPases Activate Formins
Drugs
Diseases
GWAS		Adverse response to chemotherapy (neutropenia/leucopenia) (paclitaxel) ( 23648065) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Glaucoma ( 30104761 31959993 30054594) Glaucoma (multi-trait analysis) ( 31959993) Glaucoma (primary open-angle) ( 29891935) Heel bone mineral density ( 30598549) Intraocular pressure ( 29617998 25173106 24002674 22570627 31798171 29785010 31959993 30054594 28073927 29235454) Medication use (antiglaucoma preparations and miotics) ( 31015401) Proteinuria and chronic kidney disease ( 26420894)	Asthma ( 31619474) Craniofacial microsomia ( 26853712) Hypothyroidism ( 30367059) Male-pattern baldness ( 28196072) Thyroid stimulating hormone levels ( 30367059)
Interacting Genes		20 interacting genes: ABI1 ACTA1 APBB1IP ATXN1L CREB3L2 CYFIP1 CYFIP2 DIAPH1 FMNL1 GAPDH KHDRBS1 NCKAP1 NCKAP1L NTAQ1 PACSIN1 RPLP0 SF1 SF3A1 SFPQ WASF2	10 interacting genes: APP GAS7 HMG20A PFN1 PFN2 PRPF40A RAC1 SRPK2 TCERG1 XRCC6
Entrez ID		8522	752
HPRD ID		16011	06876
Ensembl ID		ENSG00000007237	ENSG00000184922
Uniprot IDs		O60861	O95466
PDB IDs		2LX7 2YSH	4YDH
Enriched GO Terms of Interacting Partners?
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