ABT1 and CDCA7L

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ABT1	CDCA7L
Description		activator of basal transcription 1	cell division cycle associated 7 like
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex Nucleolus	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytosol
	Molecular Function	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	Protein Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of Nucleic Acid-templated Transcription	Regulation Of Transcription, DNA-templated Positive Regulation Of Cell Proliferation
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Small cell lung carcinoma ( 28604730) Waist circumference variance ( 31453325)	Breast cancer ( 29059683) Height ( 20189936) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		11 interacting genes: APP CCDC136 CDCA7L CEP70 EMD FAM9B LZTS2 PPP1CC PRNP SYNE4 TBP	38 interacting genes: ABT1 ANKRD11 AXIN1 BEND7 BYSL CARD9 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 EIF4A3 FAM9B ING5 KRTAP10-7 LMO1 MDFI MFAP1 MLH1 MORN3 MYC NOP2 PPP1R16B PRDM14 PRPF31 SSX2IP STX11 SUV39H1 TADA2A TFPT TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF821
Entrez ID		29777	55536
HPRD ID		16469	11481
Ensembl ID		ENSG00000146109	ENSG00000164649
Uniprot IDs		A0A024R029 Q9ULW3	A0A024RA51 A8K8X5 Q96GN5
PDB IDs			5YI9 6EMO
Enriched GO Terms of Interacting Partners?
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