ABT1 and SYNE4

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		ABT1	SYNE4
Description		activator of basal transcription 1	spectrin repeat containing nuclear envelope family member 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Transcription Factor Complex Nucleolus	Integral Component Of Nuclear Outer Membrane Meiotic Nuclear Membrane Microtubule Tethering Complex
	Molecular Function	DNA Binding Transcription Coactivator Activity RNA Binding Protein Binding	Protein Binding
	Biological Process	Endonucleolytic Cleavage In ITS1 To Separate SSU-rRNA From 5.8S RRNA And LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage To Generate Mature 5'-end Of SSU-rRNA From (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Endonucleolytic Cleavage In 5'-ETS Of Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Spinal Cord Motor Neuron Differentiation Small-subunit Processome Assembly Positive Regulation Of Nucleic Acid-templated Transcription	Establishment Of Epithelial Cell Apical/basal Polarity
Pathways
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Blood protein levels ( 28240269) General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Lung cancer ( 28604730) Lung cancer in ever smokers ( 28604730) Small cell lung carcinoma ( 28604730) Waist circumference variance ( 31453325)
Interacting Genes		11 interacting genes: APP CCDC136 CDCA7L CEP70 EMD FAM9B LZTS2 PPP1CC PRNP SYNE4 TBP	51 interacting genes: ABT1 ADIPOQ BRICD5 C3orf52 CD47 CEP19 CLDN7 CLDN8 CLEC7A CMTM5 CSGALNACT2 CSNK2B CXCL9 DEFB121 ECE2 EDDM3B EMP1 ENTPD3 FAM241B FATE1 GADD45A GSK3B ITM2B KLHL12 KLRG1 KTN1 MALL MARCHF2 NAGK OCLN OLFM4 OSTCP1 PAQR5 RIPPLY2 RPS6KA6 SEC22A SEC23B SENP2 SFTPC SLN SMCO4 TMEM115 TMEM140 TMEM147 TMEM182 TMEM248 TMPRSS4 TRIM69 TSPAN15 VTI1B ZNF250
Entrez ID		29777	163183
HPRD ID		16469	08776
Ensembl ID		ENSG00000146109	ENSG00000181392
Uniprot IDs		A0A024R029 Q9ULW3	Q8N205
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?