USP20 and PJA1

Number of citations of the paper that reports this interaction (PubMedID 22626734)
5

Data Source:
BioGRID (enzymatic study)

		USP20	PJA1
Description		ubiquitin specific peptidase 20	praja ring finger ubiquitin ligase 1
Image
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	G Protein-coupled Receptor Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity Protein Binding Zinc Ion Binding Thiol-dependent Ubiquitinyl Hydrolase Activity	Protein Binding Metal Ion Binding Ubiquitin Protein Ligase Activity
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Endocytosis Regulation Of G Protein-coupled Receptor Signaling Pathway Protein Deubiquitination Protein K63-linked Deubiquitination Protein K48-linked Deubiquitination	Protein Ubiquitination Protein Catabolic Process
Pathways		Ub-specific processing proteases	Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS		Metabolite levels ( 23823483)	Birth weight ( 31043758) Body mass index ( 29273807) Schizophrenia ( 25056061 29483656)
Interacting Genes		28 interacting genes: ALAS1 BEND5 BEND7 CLSPN DIO2 FATE1 GTF2IRD1 HIF1A IHO1 LMNA MAGEA11 MAPK6 MDFI PJA1 PLA2G2A PRKACA PRKCI RAD17 SPRY2 STING1 TRIM23 UBC ULK1 USP15 USP21 USP28 VAPB VHL	64 interacting genes: ABR ASCC2 ATP5F1C ATXN3 ATXN3L CAMK1G CDK16 COASY CSAG3 DDX54 EED ELAC1 ESPL1 EZH2 FGF12 GATD3A GLO1 GSR GTF2I HNRNPC HNRNPL HOMER2 JOSD1 KIF22 LCP2 LRG1 MAGEB4 MAGED1 MDM2 METAP2 NAGK NATD1 NDN OTUB1 OTUB2 PCCA PFKFB4 PHGDH PIP4K2C RIBC2 SPTBN1 STAC STAM STAMBP SUZ12 TAF9 TK1 TMEM214 TSSK3 TXNDC5 UBE2D2 UBE2D3 UBE2E3 UBE2K UBE2L3 UBE2U UCHL3 UCHL5 USP20 USP28 USP5 USP51 USP8 ZNF440
Entrez ID		10868	64219
HPRD ID		07505	02335
Ensembl ID		ENSG00000136878	ENSG00000181191
Uniprot IDs		Q9Y2K6	Q8NG27
PDB IDs		6KCZ	2L0B
Enriched GO Terms of Interacting Partners?
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