RPL6 and STAU1

Number of citations of the paper that reports this interaction (PubMedID 15121898)
60

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro)

		RPL6	STAU1
Description		ribosomal protein L6	staufen double-stranded RNA binding protein 1
Image
GO Annotations	Cellular Component	Nucleus Rough Endoplasmic Reticulum Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome	Cytoplasm Endoplasmic Reticulum Rough Endoplasmic Reticulum Cytosol Microtubule Associated Complex Plasma Membrane Cytoplasmic Stress Granule Membrane Dendrite Cytoplasmic Ribonucleoprotein Granule Neuronal Cell Body Cell Body Extracellular Exosome Glutamatergic Synapse
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Cadherin Binding	RNA Binding Double-stranded RNA Binding Protein Binding Protein Phosphatase 1 Binding
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Regulation Of Transcription, DNA-templated Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Viral Process Cellular Response To Oxidative Stress Positive Regulation Of Viral Genome Replication Positive Regulation By Virus Of Viral Protein Levels In Host Cell Modification Of Postsynaptic Structure Positive Regulation Of Long-term Synaptic Potentiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood pressure ( 21572416) Body mass index ( 26426971) Coffee consumption ( 29367735) Diastolic blood pressure ( 26390057) Esophageal cancer ( 21642993) Systolic blood pressure ( 26390057)	Anger ( 24489884) Change in quality of life in response to fluticasone propionate/salmeterol in chronic obstructive pulmonary disease ( 31299468) Cognitive ability ( 29186694) Cognitive ability (MTAG) ( 29186694) Cognitive ability, years of educational attainment or schizophrenia (pleiotropy) ( 31374203) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Height ( 28552196 25282103) Intelligence (MTAG) ( 29326435) Loneliness ( 31518406 29970889) Loneliness (MTAG) ( 29970889) Waist circumference adjusted for body mass index ( 28552196)
Interacting Genes		14 interacting genes: CSNK2A1 EIF6 FBXO7 FGF2 H2AC4 IL7R IVNS1ABP MAP3K14 MT-ND1 NFKB2 NPAS2 RPL29 SEL1L STAU1	40 interacting genes: APP CASC3 CDC42 CSNK2B DHX9 DYNC1I1 FMR1 GLRX3 HNRNPU INA IQGAP1 KIF2B LONRF1 MAP1B MAPT MYH1 NCBP1 NCL NXT1 PABPC1 PABPN1 PPP1CA PPP1CC RAC1 RASA1 ROCK2 RPL28 RPL6 RPL7A RPLP0 RPS6 SPP1 SRPK1 TAX1BP3 TINCR TUBB TUBB4A UBE2D3 UPF1 ZMAT3
Entrez ID		6128	6780
HPRD ID		04745	03422
Ensembl ID		ENSG00000089009	ENSG00000124214
Uniprot IDs		A0A024RBK3 Q02878 Q8TBK5	B3KRE0 O95793 Q59F99 Q6PJX3
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP	4DKK 6HTU
Enriched GO Terms of Interacting Partners?
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