RPL6 and SEL1L

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		RPL6	SEL1L
Description		ribosomal protein L6	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Rough Endoplasmic Reticulum Cytosol Focal Adhesion Postsynaptic Density Membrane Cytosolic Large Ribosomal Subunit Cytoplasmic Ribonucleoprotein Granule Polysomal Ribosome	Hrd1p Ubiquitin Ligase Complex Hrd1p Ubiquitin Ligase ERAD-L Complex Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Derlin-1 Retrotranslocation Complex Endoplasmic Reticulum Quality Control Compartment
	Molecular Function	DNA Binding RNA Binding Structural Constituent Of Ribosome Cadherin Binding	Protein Binding
	Biological Process	Ribosomal Large Subunit Assembly Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Cytoplasmic Translation Regulation Of Transcription, DNA-templated Translation Translational Initiation SRP-dependent Cotranslational Protein Targeting To Membrane Viral Transcription	Triglyceride Metabolic Process Notch Signaling Pathway Protein Secretion Protein Ubiquitination Ubiquitin-dependent ERAD Pathway Retrograde Protein Transport, ER To Cytosol ERAD Pathway Protein Stabilization Transmembrane Transport Endoplasmic Reticulum Mannose Trimming
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Peptide chain elongation SRP-dependent cotranslational protein targeting to membrane SRP-dependent cotranslational protein targeting to membrane Viral mRNA Translation Selenocysteine synthesis Major pathway of rRNA processing in the nucleolus and cytosol Formation of a pool of free 40S subunits GTP hydrolysis and joining of the 60S ribosomal subunit Eukaryotic Translation Termination Regulation of expression of SLITs and ROBOs Response of EIF2AK4 (GCN2) to amino acid deficiency Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Pre-NOTCH Processing in Golgi ABC-family proteins mediated transport Hedgehog ligand biogenesis Hh mutants that don't undergo autocatalytic processing are degraded by ERAD Defective CFTR causes cystic fibrosis ER Quality Control Compartment (ERQC)
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Blood pressure ( 21572416) Body mass index ( 26426971) Coffee consumption ( 29367735) Diastolic blood pressure ( 26390057) Esophageal cancer ( 21642993) Systolic blood pressure ( 26390057)	Cadmium levels ( 26025379) Intraocular pressure ( 29617998) Night sleep phenotypes ( 27126917) Periodontal disease-related phenotype (Socransky) ( 24347629)
Interacting Genes		14 interacting genes: CSNK2A1 EIF6 FBXO7 FGF2 H2AC4 IL7R IVNS1ABP MAP3K14 MT-ND1 NFKB2 NPAS2 RPL29 SEL1L STAU1	2 interacting genes: HYOU1 RPL6
Entrez ID		6128	6400
HPRD ID		04745	07532
Ensembl ID		ENSG00000089009	ENSG00000071537
Uniprot IDs		A0A024RBK3 Q02878 Q8TBK5	Q3ZCU6 Q9UBV2
PDB IDs		4UG0 4V6X 5AJ0 5LKS 5T2C 6EK0 6IP5 6IP6 6IP8 6OLE 6OLF 6OLG 6OLI 6OLZ 6OM0 6OM7 6QZP
Enriched GO Terms of Interacting Partners?
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