PTPRN and MAL

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTPRN	MAL
Description		protein tyrosine phosphatase receptor type N	mal, T cell differentiation protein
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Cell Junction Secretory Granule Transport Vesicle Membrane Neuronal Cell Body Perikaryon Axon Terminus Synapse	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding GTPase Binding	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath
	Biological Process	Response To Reactive Oxygen Species Luteinization Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Peptidyl-tyrosine Dephosphorylation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252)
Interacting Genes		13 interacting genes: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4	10 interacting genes: EDA FIBCD1 KLRC1 LDLRAD1 LMNA LSMEM1 MYD88 PTPRN SMIM3 USP7
Entrez ID		5798	4118
HPRD ID		03466	01789
Ensembl ID		ENSG00000054356	ENSG00000172005
Uniprot IDs		Q16849 Q96IA0	A0A024RE19 P21145
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5
Enriched GO Terms of Interacting Partners?
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