PTPRN and PTPRT

Number of citations of the paper that reports this interaction (PubMedID 16273344)
8

Data Source:
HPRD (two hybrid, in vitro)

		PTPRN	PTPRT
Description		protein tyrosine phosphatase receptor type N	protein tyrosine phosphatase receptor type T
Image
GO Annotations	Cellular Component	Cell Nucleus Endosome Golgi Apparatus Plasma Membrane Synaptic Vesicle Integral Component Of Membrane Cell Junction Secretory Granule Transport Vesicle Membrane Neuronal Cell Body Perikaryon Axon Terminus Synapse	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protein Tyrosine Phosphatase Activity Protein Binding Transcription Factor Binding Spectrin Binding Ubiquitin-like Protein Ligase Binding GTPase Binding	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Protein Binding Beta-catenin Binding Protein Phosphatase Binding Protein Homodimerization Activity Alpha-catenin Binding Gamma-catenin Binding Cadherin Binding Delta-catenin Binding STAT Family Protein Binding
	Biological Process	Response To Reactive Oxygen Species Luteinization Cytokine-mediated Signaling Pathway Insulin Secretion Response To Insulin Peptidyl-tyrosine Dephosphorylation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Response To Estrogen Positive Regulation Of Transcription By RNA Polymerase II Response To CAMP Positive Regulation Of Type B Pancreatic Cell Proliferation Dense Core Granule Maturation	Protein Dephosphorylation Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Cell Migration Peptidyl-tyrosine Dephosphorylation Cellular Response To Interleukin-6 Negative Regulation Of STAT Cascade Peptidyl-tyrosine Dephosphorylation Involved In Inactivation Of Protein Kinase Activity
Pathways
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252)	Age-related nuclear cataracts ( 24951543) Anxiety and stress-related disorders ( 31116379) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Eye morphology ( 29921221) Facial attractiveness (male raters) ( 30946739) Fractional exhaled nitric oxide (childhood) ( 24315451) Hip circumference ( 28552196) Household income (MTAG) ( 31844048) Metabolite levels ( 23823483) Microalbuminuria ( 26631737) Periodontitis (Mean PAL) ( 24024966) Problematic alcohol use in trauma-exposed individuals ( 29082582) Recurrence of malaria infection (mild or asymptomatic) ( 31667592) Recurrence of mild malaria attacks ( 31667592) Serum bilirubin levels x Mediterranean diet adherence interaction in metabolic syndrome ( 30621171) Systolic blood pressure ( 27841878) Temporal pole volume ( 31530798) Urate levels in obese individuals ( 25811787) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683) Weight ( 28552196)
Interacting Genes		13 interacting genes: CAPN2 CLN8 MADD MAL NOS1 PLP1 PPIA PTPRS PTPRT SNTB2 SNX19 SPTBN4 UBQLN4	5 interacting genes: EGFR ERBB2 ERBB4 IL17RA PTPRN
Entrez ID		5798	11122
HPRD ID		03466	06690
Ensembl ID		ENSG00000054356	ENSG00000196090
Uniprot IDs		Q16849 Q96IA0	A0A075B6H0 O14522
PDB IDs		2I1Y 2QT7 3N01 3N4W 3NG8 3NP5	2OOQ
Enriched GO Terms of Interacting Partners?
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