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MAL and USP7
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
75
Data Source:
BioGRID
(two hybrid)
MAL
USP7
Description
mal, T cell differentiation protein
ubiquitin specific peptidase 7
Image
No pdb structure
GO Annotations
Cellular Component
Endoplasmic Reticulum
Integral Component Of Membrane
Apical Plasma Membrane
Extrinsic Component Of Membrane
Plasma Membrane Raft
Membrane Raft
Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane
Nucleus
Nucleoplasm
Chromosome
Cytosol
Nuclear Body
PML Body
Protein-containing Complex
Molecular Function
Protein Binding
Lipid Binding
Peptidase Activator Activity Involved In Apoptotic Process
Structural Constituent Of Myelin Sheath
P53 Binding
Cysteine-type Endopeptidase Activity
Thiol-dependent Ubiquitin-specific Protease Activity
Protein Binding
Protein C-terminus Binding
Transcription Factor Binding
Ubiquitin Protein Ligase Binding
Thiol-dependent Ubiquitinyl Hydrolase Activity
Ubiquitinyl Hydrolase Activity
Lys48-specific Deubiquitinase Activity
Biological Process
Membrane Raft Polarization
Protein Localization To Paranode Region Of Axon
Apoptotic Process
Central Nervous System Development
Cell Differentiation
Myelination
Apical Protein Localization
Protein Insertion Into Plasma Membrane
Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Gluconeogenesis
Transcription-coupled Nucleotide-excision Repair
Ubiquitin-dependent Protein Catabolic Process
Multicellular Organism Development
Maintenance Of DNA Methylation
Viral Process
Protein Ubiquitination
Protein Deubiquitination
Regulation Of Protein Stability
Negative Regulation Of NF-kappaB Transcription Factor Activity
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Monoubiquitinated Protein Deubiquitination
Histone H2B Conserved C-terminal Lysine Deubiquitination
Regulation Of Circadian Rhythm
Rhythmic Process
Protein Stabilization
Regulation Of DNA-binding Transcription Factor Activity
Protein K63-linked Deubiquitination
Protein K48-linked Deubiquitination
Positive Regulation Of DNA Demethylation
Regulation Of Telomere Capping
Pathways
Ub-specific processing proteases
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Regulation of TP53 Degradation
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Regulation of PTEN localization
Drugs
Diseases
GWAS
Chronotype (
30696823
)
Platelet count (
27863252
)
Platelet distribution width (
27863252
)
Interacting Genes
10 interacting genes:
EDA
FIBCD1
KLRC1
LDLRAD1
LMNA
LSMEM1
MYD88
PTPRN
SMIM3
USP7
99 interacting genes:
ABRAXAS2
ACD
ANXA1
ARNT2
ATXN1
BCOR
BEND5
CBX8
CHEK1
CLSPN
CREB3L3
CRY1
CSNK2A1
CTNNB1
DAXX
DNAJA3
DNMT3A
EWSR1
EZH2
FOXN2
GATA1
H2AC20
H2BU1
HECW1
HERPUD1
HIF1A
HTRA2
HUWE1
IFNAR1
KAT5
KDM1A
KLHL8
MAGEE1
MAL
MARCHF7
MCMBP
MDM2
MDM4
MYC
MYD88
NECAB2
NOTCH1
OTUD4
PCGF2
PEG3
PEPD
PHF8
PHLDB2
PICK1
PLA2G2A
PLEKHO1
POLH
PPARG
PPL
PTEN
RAD18
RADIL
RARA
RB1
RBCK1
RELA
RFFL
RNF168
RNF220
SCML2
SIRT7
SMAD3
SNCA
SUMO2
SYVN1
TANK
TBCB
TFIP11
TMPO
TP53
TRAF1
TRAF2
TRAF3
TRAF4
TRAF5
TRAF6
TRIM22
TRIM31
TRIM54
TRIM55
TRIM63
TRIM8
TRO
UBA52
UBC
UBE2D3
UBE2E1
UBE2S
USP21
USP28
WWP2
XPC
ZMYND8
ZNF423
Entrez ID
4118
7874
HPRD ID
01789
03950
Ensembl ID
ENSG00000172005
ENSG00000187555
Uniprot IDs
A0A024RE19
P21145
B7Z855
B7ZAX6
Q6U8A4
Q93009
PDB IDs
1NB8
1NBF
1YY6
1YZE
2F1W
2F1X
2F1Y
2F1Z
2FOJ
2FOO
2FOP
2KVR
2XXN
2YLM
3MQR
3MQS
4JJQ
4KG9
4M5W
4M5X
4PYZ
4WPH
4WPI
4YOC
4YSI
4Z96
4Z97
5C56
5C6D
5FWI
5GG4
5J7T
5JTJ
5JTV
5KYB
5KYC
5KYD
5KYE
5KYF
5N9R
5N9T
5NGE
5NGF
5UQV
5UQX
5VS6
5VSB
5VSK
5WHC
6F5H
Enriched GO Terms of Interacting Partners
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