MAL and SMIM3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MAL	SMIM3
Description		mal, T cell differentiation protein	small integral membrane protein 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Integral Component Of Membrane Apical Plasma Membrane Extrinsic Component Of Membrane Plasma Membrane Raft Membrane Raft Hinge Region Between Urothelial Plaques Of Apical Plasma Membrane	Integral Component Of Membrane
	Molecular Function	Protein Binding Lipid Binding Peptidase Activator Activity Involved In Apoptotic Process Structural Constituent Of Myelin Sheath	Protein Binding
	Biological Process	Membrane Raft Polarization Protein Localization To Paranode Region Of Axon Apoptotic Process Central Nervous System Development Cell Differentiation Myelination Apical Protein Localization Protein Insertion Into Plasma Membrane Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Pathways
Drugs
Diseases
GWAS			Cholangiocarcinoma in primary sclerosing cholangitis ( 28779025) Crohn's disease ( 28067908) Dimensional psychopathology (Arousal) ( 29496196) Inflammatory bowel disease ( 28067908)
Interacting Genes		10 interacting genes: EDA FIBCD1 KLRC1 LDLRAD1 LMNA LSMEM1 MYD88 PTPRN SMIM3 USP7	10 interacting genes: ATP6V0C BSCL2 CLEC7A EMP1 LZTS2 MAL PMP22 PNMA1 SFTPC TRIM14
Entrez ID		4118	85027
HPRD ID		01789	12212
Ensembl ID		ENSG00000172005	ENSG00000256235
Uniprot IDs		A0A024RE19 P21145	Q9BZL3
PDB IDs
Enriched GO Terms of Interacting Partners?
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