AGTRAP and AGTR2

Number of citations of the paper that reports this interaction (PubMedID 11733189)
6

Data Source:
BioGRID (pull down)

		AGTRAP	AGTR2
Description		angiotensin II receptor associated protein	angiotensin II receptor type 2
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Cell Plasma Membrane Integral Component Of Plasma Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	G Protein-coupled Receptor Activity Angiotensin Type II Receptor Activity Protein Binding Transcription Factor Binding Receptor Antagonist Activity
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Blood Vessel Remodeling Regulation Of Systemic Arterial Blood Pressure By Circulatory Renin-angiotensin Renin-angiotensin Regulation Of Aldosterone Production Angiotensin-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Brain Renin-angiotensin System Cellular Sodium Ion Homeostasis Inflammatory Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Coupled To CGMP Nucleotide Second Messenger Nitric Oxide Mediated Signal Transduction Brain Development Regulation Of Blood Pressure Positive Regulation Of Cell Proliferation Negative Regulation Of Heart Rate Negative Regulation Of Norepinephrine Secretion Cerebellar Cortex Development Negative Regulation Of Cell Growth Negative Regulation Of Icosanoid Secretion Positive Regulation Of Phosphoprotein Phosphatase Activity Intracellular Signal Transduction Regulation Of Metanephros Size Exploration Behavior Positive Regulation Of Renal Sodium Excretion Aldosterone Secretion Angiotensin-activated Signaling Pathway Regulation Of Protein Import Into Nucleus Vasodilation Dopamine Biosynthetic Process Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Fibroblast Proliferation Positive Regulation Of Cytokine Secretion Positive Regulation Of Nitric-oxide Synthase Activity Negative Regulation Of Neurotrophin TRK Receptor Signaling Pathway Cell Growth Involved In Cardiac Muscle Cell Development Cellular Response To Dexamethasone Stimulus Positive Regulation Of Metanephric Glomerulus Development Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Positive Regulation Of Blood Vessel Diameter Negative Regulation Of Signaling Receptor Activity Positive Regulation Of Extrinsic Apoptotic Signaling Pathway
Pathways		Signaling by BRAF and RAF fusions	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs			Tasosartan CYT006-AngQb
Diseases			Non-syndromic X-linked mental retardation
GWAS		Systolic blood pressure ( 19430483)	Cystic fibrosis severity ( 21602797) Gestational age at birth (maternal effect) ( 28877031) Lung disease severity in cystic fibrosis ( 26417704) Offspring birth weight ( 31043758) Preterm birth (maternal effect) ( 28877031) Type 2 diabetes ( 29358691 30130595)
Interacting Genes		79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391	11 interacting genes: ACE AGT AGTRAP ERBB3 ERBIN GNAI2 GNAI3 MTUS1 PIK3CB SNTA1 ZBTB16
Entrez ID		57085	186
HPRD ID		16379	02071
Ensembl ID		ENSG00000177674	ENSG00000180772
Uniprot IDs		Q6RW13	P50052
PDB IDs			5UNF 5UNG 5UNH
Enriched GO Terms of Interacting Partners?
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