AGTRAP and SUCLA2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		AGTRAP	SUCLA2
Description		angiotensin II receptor associated protein	succinate-CoA ligase ADP-forming subunit beta
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Mitochondrion Mitochondrial Matrix Succinate-CoA Ligase Complex Extracellular Exosome
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Protein Binding ATP Binding
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Succinyl-CoA Pathway
Pathways		Signaling by BRAF and RAF fusions	Citric acid cycle (TCA cycle)
Drugs			Succinic acid
Diseases			Mitochondrial DNA depletion syndrome (MDS)
GWAS		Systolic blood pressure ( 19430483)	Aging (time to event) ( 21782286) Colorectal cancer (diet interaction) ( 24743840) Thiopurine-induced acute severe leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced early leukopenia in Crohn's disease ( 25108385) Thiopurine-induced leukopenia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe alopecia in inflammatory bowel disease ( 29923122) Thiopurine-induced severe leukopenia in inflammatory bowel disease ( 29923122) Visceral adipose tissue adjusted for BMI ( 22589738) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)
Interacting Genes		79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391	6 interacting genes: AGTRAP ALAS2 ARL6IP1 CMTM5 FAM9B MTNR1A
Entrez ID		57085	8803
HPRD ID		16379	06798
Ensembl ID		ENSG00000177674	ENSG00000136143
Uniprot IDs		Q6RW13	E5KS60 Q9P2R7 Q9Y4T0
PDB IDs			6G4Q
Enriched GO Terms of Interacting Partners?
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