AGTRAP and PNPO

Number of citations of the paper that reports this interaction (PubMedID 25910212)
127

Data Source:
BioGRID (two hybrid)

		AGTRAP	PNPO
Description		angiotensin II receptor associated protein	pyridoxamine 5'-phosphate oxidase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Nucleoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cell Cortex Integral Component Of Membrane Cytoplasmic Vesicle Membrane Intracellular Membrane-bounded Organelle	Nucleoplasm Cytosol
	Molecular Function	Angiotensin Type II Receptor Activity Protein Binding	Pyridoxamine-phosphate Oxidase Activity Protein Binding FMN Binding Pyridoxal Phosphate Binding Protein Homodimerization Activity
	Biological Process	Response To Hypoxia Regulation Of Blood Pressure Angiotensin-activated Signaling Pathway	Pyridoxine Biosynthetic Process Vitamin B6 Metabolic Process Pyridoxal Phosphate Biosynthetic Process Oxidation-reduction Process
Pathways		Signaling by BRAF and RAF fusions	Vitamins B6 activation to pyridoxal phosphate
Drugs			Pyridoxal Phosphate Riboflavin Monophosphate Beta-Mercaptoethanol
Diseases
GWAS		Systolic blood pressure ( 19430483)	Body mass index ( 26426971) Generalized epilepsy ( 30531953 22949513)
Interacting Genes		79 interacting genes: ACSF2 AGTR1 AGTR2 ALDH18A1 AP3M1 ARAF ARFIP2 ARHGAP1 BPIFA2 CAPNS1 CD160 CIAO2A COQ8A CPLX1 CRCT1 DDA1 DDX55 DGCR6 DIABLO ECPAS FAM114A1 FAM160A2 FARS2 FASTKD3 FATE1 FGA GABARAPL2 GAD1 GAD2 GDNF GTF3C1 H4C7 HARS2 HMGB1 HSCB HSPA4 ISCU LMNA LMO2 LNX1 MCEE MIEF1 MIEF2 MRM1 MTERF3 MUTYH MYG1 NDRG4 NFU1 NFYB NKG7 PBX3 PCTP PDHX PIMREG PITPNC1 PNPO PTPN9 RACK1 RMDN2 S100B SENP2 SNX1 SPG21 SSX3 SSX5 STAG3L1 SUCLA2 SYT16 TBRG4 TCEANC2 TFAM TMEM14B TPD52L3 TUBA1B TXN2 UBE2I ZFYVE21 ZNF391	3 interacting genes: AGTRAP APP CMTM5
Entrez ID		57085	55163
HPRD ID		16379	04476
Ensembl ID		ENSG00000177674	ENSG00000108439
Uniprot IDs		Q6RW13	Q9NVS9 V9HW45
PDB IDs			1NRG 3HY8 6H00
Enriched GO Terms of Interacting Partners?
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