TWF1 and ACTC1

Number of citations of the paper that reports this interaction (PubMedID 12207032)
18

Data Source:
HPRD (in vivo)

		TWF1	ACTC1
Description		twinfilin actin binding protein 1	actin alpha cardiac muscle 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Cytosol Actin Filament Cell-cell Junction Focal Adhesion Actin Cytoskeleton Myofibril Filopodium Ruffle Membrane Perinuclear Region Of Cytoplasm	Extracellular Space Cytoplasm Cytosol Actin Filament Focal Adhesion Actin Cytoskeleton Membrane Sarcomere Lamellipodium Filopodium I Band Actomyosin, Actin Portion Cell Body Extracellular Exosome Blood Microparticle Glutamatergic Synapse
	Molecular Function	Actin Binding Actin Monomer Binding Protein Tyrosine Kinase Activity Protein Binding ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Cadherin Binding Actin Filament Binding	ATP Binding ATPase Activity Myosin Binding
	Biological Process	Regulation Of Lamellipodium Assembly Positive Regulation Of Neuron Projection Development Peptidyl-tyrosine Phosphorylation Actin Filament Depolymerization Negative Regulation Of Actin Filament Polymerization Sequestering Of Actin Monomers Regulation Of Actin Phosphorylation Barbed-end Actin Filament Capping	Actin Filament Organization Positive Regulation Of Gene Expression Actin Filament-based Movement Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Actomyosin Structure Organization Actin-myosin Filament Sliding Negative Regulation Of Apoptotic Process Response To Ethanol Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Heart Contraction Cardiac Muscle Contraction Mesenchyme Migration
Pathways			Striated Muscle Contraction
Drugs
Diseases			Hypertrophic cardiomyopathy (HCM) Atrial septal defect Dilated cardiomyopathy (DCM)
GWAS		Inflammatory bowel disease ( 27569725)	Axial length ( 24144296) Refractive error ( 20835239)
Interacting Genes		4 interacting genes: ACTC1 APP BMPR2 FBXO25	39 interacting genes: ABLIM3 ABRA ACTB ACTN4 ACTR2 AFAP1 ANG BCL11A CAPN1 CFL1 DMD DMTN DYNLL1 EZR FBXO7 FSCN1 GAPDH GC HSPB1 HSPB2 KAT14 KLHL17 KLHL2 KPTN LASP1 MIB2 MPC1 MYLK PLEC PRKCE SCIN SLC4A1 SYNE1 SYNE2 TNNI3K TWF1 UBC WAS WIPF1
Entrez ID		5756	70
HPRD ID		10174	00015
Ensembl ID		ENSG00000151239	ENSG00000159251
Uniprot IDs		Q12792	B3KPP5 P68032
PDB IDs
Enriched GO Terms of Interacting Partners?
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