PTGER3 and TRIM42

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		PTGER3	TRIM42
Description		prostaglandin E receptor 3	tripartite motif containing 42
Image			No pdb structure
GO Annotations	Cellular Component	Cell Nuclear Envelope Plasma Membrane Integral Component Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Prostaglandin E Receptor Activity	Protein Binding Zinc Ion Binding
	Biological Process	Inflammatory Response G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Death Intestine Smooth Muscle Contraction Positive Regulation Of Fever Generation Negative Regulation Of Gastric Acid Secretion
Pathways		Prostanoid ligand receptors G alpha (i) signalling events
Drugs		Bimatoprost Dinoprostone Misoprostol Gemeprost Limaprost
Diseases
GWAS		Dental caries (decayed, missing and filled teeth) ( 31533690) Intelligence (MTAG) ( 29326435) Verbal declarative memory ( 25648963)	Bipolar disorder (body mass index interaction) ( 24322204) Refractive astigmatism ( 25367360)
Interacting Genes		23 interacting genes: ADAMTSL4 CCDC33 CDA EFEMP2 INCA1 KRT31 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 MEOX2 MGAT5B MKLN1 NOTCH2NLA PTGER1 REL RGS17 RGS20 SPRY2 TCF4 TRIM42	64 interacting genes: ADAMTSL4 ARMC7 ARNT2 ARRDC3 AXIN1 BEX2 C1orf109 CARD9 CBY2 CCDC33 CDCA7L CEP70 EFHC2 EMD GLI1 GLRX3 GLYCTK GOLGA2 HOXA1 IHO1 IKZF3 IQUB KCTD9 KLHL38 KRT13 KRT15 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-9 KRTAP26-1 KRTAP3-2 KRTAP4-2 L3MBTL2 LONRF1 LZTS2 MAGOHB MEOX2 MFAP1 MID2 MTUS2 MVP NOTCH2NLA PLSCR1 PNMA1 PSMA1 PSMD9 PTGER3 RAMAC RCOR3 RUNX1T1 SCNM1 SSX2IP STK16 TASOR2 TRAF1 TRAF2 TRAPPC2B TRIM23 TRIM27 TXNDC5 VPS37A YWHAQ ZBTB1
Entrez ID		5733	287015
HPRD ID		08906	15559
Ensembl ID		ENSG00000050628	ENSG00000155890
Uniprot IDs		O00325 P43115	Q8IWZ5
PDB IDs		6AK3 6M9T
Enriched GO Terms of Interacting Partners?
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